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06-1049

Sigma-Aldrich

Anti-Axin-1 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Axin-1, Axis inhibition protein 1, hAxin

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_003493

UniProt accession no.

O15169

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Anti-Cytomegalovirus Antibody, pp65, clone 12D10

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biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

clone

422-8D-4C-4D, monoclonal

clone

7/48.7c, monoclonal

clone

12D10, monoclonal

clone

231-9F, monoclonal, 233-4D, monoclonal, 251-12A, monoclonal, 341-7H, monoclonal, 343-5G, monoclonal, 354-8B, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

ELISA: suitable, immunofluorescence: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

General description

Axin-1 is a beta-catenin destruction complex scaffold protein and a transcription factor of the Wnt signaling pathway. Variation in the Wnt signaling pathway has been associated with the formation of some primary human cancers. Axin-1 mutation has been linked to oral squamous cell carcinoma. Axin-1 binds to GSK3alpha and activates the Wnt signaling pathway which is shown to be associated with growth and development of cells. Axin-1 has also been implicated in Alzheimer′s disease.

Immunogen

KLH-conjugated linear peptide corresponding to human Axin-1.

Application

Anti-Axin-1 Antibody is an antibody against Axin-1 for use in WB, IC, IH.
Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected Axin-1 in A431 and HeLa cells.

Immunohistochemistry Analysis: 1:1,000 dilution from a representative lot detected Axin-1 in human kidney and human skin tissues.

Quality

Evaluated by Western Blot in HEK293 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Axin-1 on 10 µg of HEK293 cell lysate.

Target description

~110 kDa observed. An uncharacterized band appears at ~40 and 45 kDa in some lysates.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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