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1.06756

SAFC

Methyl 4-hydroxybenzoate sodium salt

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

Synonym(s):

Methyl 4-hydroxybenzoate sodium salt, 4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt

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About This Item

Linear Formula:
Na+[4-(O)C6H4(COOCH3)]-
CAS Number:
5026-62-0
Molecular Weight:
174.13
MDL number:
MFCD00016470
UNSPSC Code:
12352108
EC Index Number:
225-714-1
Pricing and availability is not currently available.

agency

BP
NF
Ph. Eur.

Quality Level

500

product line

EMPROVE® ESSENTIAL

form

solid

autoignition temp.

>600 °C

pH

9.7-10.3 (1 g/L in H2O)

mp

>125 °C

density

1.42 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

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1 of 4

This Item
1.074281.067571.00886
Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

1.06756

Methyl 4-hydroxybenzoate sodium salt

Propyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

1.07428

Propyl 4-hydroxybenzoate sodium salt

Methyl 4-hydroxybenzoate EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, NF

1.06757

Methyl 4-hydroxybenzoate

Ethyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

1.00886

Ethyl 4-hydroxybenzoate sodium salt

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

application(s)

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
solid formulation

application(s)

liquid formulation
ophthalmics
pharmaceutical

agency

BP, Ph. Eur., NF

agency

BP, NF, Ph. Eur.

agency

BP, ChP, JP, NF, Ph. Eur.

agency

BP, NF, Ph. Eur.

form

solid

form

solid

form

solid

form

solid

density

1.42 g/cm3 at 20 °C

density

1.24 g/cm3 at 25 °C

density

1.38 g/cm3 at 20 °C

density

-

product line

EMPROVE® ESSENTIAL

product line

EMPROVE® ESSENTIAL

product line

EMPROVE® EXPERT

product line

EMPROVE® ESSENTIAL

autoignition temp.

>600 °C

autoignition temp.

-

autoignition temp.

>600 °C

autoignition temp.

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Methyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like propyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard methyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

pictograms

Corrosion
GHS05

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

    • What is the Emprove® Program?

    The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

    Material Qualification Dossier

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    Quality Management Dossier

    Available by subscription or for a fee

    Operational Excellence Dossier

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    Why are these documents unavailable?
    Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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    Sigma-Aldrich

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