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1.15684

Supelco

TLC plates, Silica gel 60 RP-8 F₂₅₄s

pkg of 25 plates, plate L × W 5 cm × 10 cm, glass support

Synonym(s):

RP-8 Silica Gel Thin-layer Chromatography Plates

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About This Item

UNSPSC Code:
41115711
NACRES:
NB.21

Pricing and availability is not currently available.

material

glass support
silica gel 60 matrix

Quality Level

feature

binder Organic Polymer
fluorescent indicator

packaging

pkg of 25 plates

technique(s)

thin layer chromatography (TLC): suitable

layer thickness

250 μm

plate L × W

5 cm × 10 cm

particle size

10-12 μm

pore size

60 Å medium pore diameter

storage temp.

2-30°C

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This Item
1.154241.153881.05560
technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

material

glass support, silica gel 60 matrix

material

glass support, silica gel 60 matrix

material

glass support, silica gel 60 matrix

material

aluminum support, silica gel 60 matrix

feature

fluorescent indicator, binder Organic Polymer

feature

binder Organic Polymer, fluorescent indicator

feature

binder Organic Polymer, fluorescent indicator

feature

binder Organic Polymer, fluorescent indicator

pore size

60 Å medium pore diameter

pore size

60 Å medium pore diameter

pore size

60 Å medium pore diameter

pore size

60 Å medium pore diameter

packaging

pkg of 25 plates

packaging

pkg of 50 plates

packaging

pkg of 25 plates

packaging

pkg of 20 sheets

layer thickness

250 μm

layer thickness

250 μm

layer thickness

250 μm

layer thickness

200 μm

General description

25 Glass plates 5 x 10 cm
RP modified plates serve two purposes: act as a pilot method for HPLC and allow to choose various solvent system for special separations. Our RP-modified silica layers are well suited for many separation challenges that unmodified silica cannot overcome. These layers use aqueous solvent systems to separate extremely non-polar substances and analyze particular polar substances that can adapt to ion-pair chromatography. What’s more, RP-modified silica layers are less dependent on atmospheric humidity. Unlike unmodified silica, RP-phases do not exhibit catalytic activity. This makes them the plates of choice for unstable substance that tend to experience oxidative degradation.

Application

Glass TLC plates, RP-8 modified silica gel coated with flourescent indicator F254s. The RP-8 modified silica gel TLC plates come in a quantity of 25 size 5x10 cm for thin layer chromatography applications.

Linkage

Replaces: 15684-1; 15684

Analysis Note

Specific surface area (according to BET; 5-Pt. measurement): 480 - 540 m²/g
Pore volume (N₂-isotherm): 0.74 - 0.84 ml/g
d 50 (laser diffraction, size distribution): 9.5 - 11.5 µm
Layer thickness: 200 - 270 µm
Deviation of layer thickness per plate: ≤ 35 µm
Chromatographic testings:
A) Cholesterin test
hRf-values
- cholesterin, cholesterin test:
68 - 74
B) Steroid test
- methyltestosterone, steroid test: 45 - 55
- Reichstein S, steroid test: 65 - 75
- hydrocortisone, steroid test: 75 - 91
Typical value determined on an activated plate (120°C, 15 min)
Eluent a) aceton/ water (95/5 v/v)
Eluent b) acetonitrile/ water (70/30 v/v)

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Karsten Weller et al.
Acta dermato-venereologica, 93(2), 168-174 (2012-10-12)
Non-sedating H1-antihistamines are the recommended first-line treatment for chronic spontaneous urticaria. While efficacy studies usually apply continuous daily treatment regimens, many patients take their medication on demand. In this randomized, double-blind trial we tested whether on-demand H1-antihistamine desloratadine in standard
P Deep et al.
Synapse (New York, N.Y.), 34(4), 313-318 (1999-10-26)
The efficacy of amantadine in alleviating motor symptoms of Parkinson's disease may be mediated in part by stimulation of cerebral dopa decarboxylase (DDC) activity, secondary to antagonism of N-methyl-D-aspartate (NMDA) type glutamate receptors. We tested the specific hypothesis that amantadine
F Estelle R Simons et al.
The Journal of allergy and clinical immunology, 110(5), 777-783 (2002-11-06)
The extent of the distribution of H(1)- antihistamines into the skin and H(1)-antihistamine activity in the skin are clinically relevant in the treatment of allergic skin disorders. In a prospective, randomized, double-blind, parallel-group, multiple-dose study, we gave fexofenadine 180 mg
M Magerl et al.
The British journal of dermatology, 166(5), 1095-1099 (2012-01-17)
Cold urticaria is a rare but severe and potentially lethal condition. It is primarily treated symptomatically with H(1) -antihistamines. However, patients have a variable response to these drugs and, to date, it has not been possible to predict readily the
Mohamed El-Awady et al.
Journal of chromatography. A, 1309, 64-75 (2013-08-21)
The analysis of hydrophobic basic analytes by micellar electrokinetic chromatography (MEKC) is usually challenging because of the tendency of these analytes to be adsorbed onto the inner capillary wall in addition to the difficulty to separate these compounds as they

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