recombinant
expressed in baculovirus infected Sf21 cells
Quality Level
description
protein target EphA4
purified by
(Ni2+/NTA-agarose)
technique(s)
activity assay: suitable
UniProt accession no.
Gene Information
human ... EPHA4(2043)
General description
SIZE: 986 amino acids; 109860 Da
SUBUNIT: Interacts with the src family kinase, p59-Fyn, through the major phosphorylation site at position Tyr-602. Interacts with NGEF/ephexin-1 (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Ubiquitous.
DOMAIN: SwissProt: P54764 The protein kinase domain mediates interaction with NGEF/ephexin-1 (By similarity).
SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.
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Analysis Note
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