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Sigma-Aldrich

Peroxynitrite

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About This Item

UNSPSC Code:
41116012
eCl@ss:
32160405
NACRES:
NA.41
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form

liquid

Quality Level

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

shipped in

dry ice

General description

Peroxynitrite (ONOO−) is a powerful oxidant formed by the collision of nitric oxide and superoxide.

Application

Peroxynitrite has been used to induce pericyte contraction in mouse brains. It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies.

Biochem/physiol Actions

Peroxynitrite (ONOO−) exhibits bactericidal activity. It promotes cell death and contributes to the signal-transduction process, mitochondrial function, and apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseases, ischemia-reperfusion injury, circulatory shock, inflammation, pain, and neurodegeneration.

Quality

Routinely evaluated by treating non-stimulated A431 cells.

Physical form

0.3M NaOH

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Corrosion

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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