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N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt

Inhibitor of bacterial, viral, and mammalian neuraminidases. Ki = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.

Synonym(s):

N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt

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About This Item

Empirical Formula (Hill Notation):
C11H16NNaO8
Molecular Weight:
313.24
UNSPSC Code:
12352201
NACRES:
NA.79
Pricing and availability is not currently available.

Quality Level

100

assay

≥95% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

off-white to pale yellow

solubility

water: 1 mM

shipped in

ambient

storage temp.

−20°C

General description

A ganglioside neuraminidase inhibitor that is believed to act by binding to the catalytic site of neuraminidase. Reported to inhibit influenza virus neuraminidase (Ki = 4 µM). Also inhibits bacterial, viral, and mammalian neuraminidases.
Inhibitor of bacterial, viral, and mammalian neuraminidases. Ki = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Kopitz, J., et al. 1997. Eur. J. Cell. Biol.73, 1.
Holzer, C.T., et al. 1993. Glycoconj. J.10, 40.
Chong, A.K., et al. 1991. Biochem. Int.24, 165.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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