516485
Pepstatin A Methyl Ester
A cell-permeable methyl ester derivative of Pepstatin A that acts as a potent, non-competitive, transition-state analog inhibitor of γ-secretase.
Synonym(s):
Pepstatin A Methyl Ester, Isovaleryl-V V-Sta-A-Sta-OCH₃, PME
About This Item
Quality Level
assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
DMSO: 5 mg/mL
shipped in
wet ice
storage temp.
−20°C
1 of 4
This Item | 1.07667 | 1.07237 | 1.07232 |
---|---|---|---|
form powder (dehydrated (DCM)) | form medium granules (dehydrated (DCM)) | form medium granules (dehydrated (DCM)) | form medium granules (dehydrated (DCM)) |
technique(s) microbiological culture: suitable | technique(s) microbiological culture: suitable | technique(s) microbiological culture: suitable | technique(s) microbiological culture: suitable |
suitability Enterobacter spp., Escherichia coli | suitability Salmonella spp., Shigella spp. | suitability Salmonella spp. | suitability Salmonella spp. |
application(s) clinical | application(s) food and beverages | application(s) clinical | application(s) clinical |
solubility 36 g/L | solubility 60 g/L | solubility 52 g/L | solubility 52 g/L |
pH 7.1 (37 °C, 36 g/L in H2O, after autoclaving) | pH 7.0-7.2 (37 °C, 60 g/L in H2O, after autoclaving) | pH 6.7-7.1 (25 °C in H2O) | pH 6.8-7.0 (37 °C, 52 g/L in H2O, after autoclaving) |
General description
Biochem/physiol Actions
γ-secretase
Packaging
Warning
Reconstitution
Other Notes
Zhang, L., et al. 2001. Biochemistry40, 5049.
Murphy, M.P., et al. 1999. J. Biol. Chem.274, 11914.
Legal Information
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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