Skip to Content
MilliporeSigma

Skip To

605160

Sigma-Aldrich

Thrombin, Plasminogen-Free, Bovine

Synonym(s):

Thrombin, Plasminogen-Free, Bovine

Sign Into View Organizational & Contract Pricing

About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.25
Pricing and availability is not currently available.
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

description

Merck USA index - 14, 9383

Quality Level

form

lyophilized

specific activity

≥1000 NIH units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated

solubility

water: 1 mg/mL

foreign activity

Plasminogen, none detected (by rocket IEP)

shipped in

ambient

storage temp.

−20°C

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
T7326T6634T4648
specific activity

≥1000 NIH units/mg protein

specific activity

≥60 NIH units/mg protein (biuret)

specific activity

600-2,000 NIH units/mg protein (biuret)

specific activity

40-500 NIH units/mg protein (biuret)

form

lyophilized

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

shipped in

ambient

shipped in

-

shipped in

-

shipped in

wet ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

OK to freeze, desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

water: 1 mg/mL

solubility

-

solubility

-

solubility

-

General description

Native, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin. Serine protease formed in the plasma during the coagulation process by activation of prothrombin by a complex of Factor Xa, Factor Va, phospholipid, and Ca2+. Thrombin cleaves Arg-Gly bonds in specific sequences only. The best characterized activity of thrombin is the conversion of fibrinogen to fibrin in the clotting process. Inhibited by AEBSF (Cat. No. 101500) Antithrombin (Cat. No. 169756), PMSF (Cat. No. 52332), and TLCK (Cat. No. 616382). Note: 1 KU = 1000 units.

Warning

Toxicity: Harmful (C)

Unit Definition

One unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.

Physical form

Lyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.

Reconstitution

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.

Analysis Note

Complete activation from homogeneous bovine prothrombin by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


  • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service