8.09622
Ethyl acetoacetate
for synthesis
Synonym(s):
Ethyl acetoacetate, EAA, Acetoacetic acid ethyl ester
Sign Into View Organizational & Contract Pricing
Select a Size
All Photos(1)
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C6H10O3
CAS Number:
Molecular Weight:
130.14
MDL number:
UNSPSC Code:
12352108
EC Index Number:
205-516-1
NACRES:
NA.22
vapor pressure
0.26 hPa ( 20 °C)
Quality Level
assay
≥98.0% (GC)
form
liquid
autoignition temp.
350 °C
potency
3980 mg/kg LD50, oral (Rat)
>5000 mg/kg LD50, skin (Rabbit)
expl. lim.
1.0-54 % (v/v)
pH
4.0 (20 °C, 110 g/L in H2O)
mp
-53.3 °C
transition temp
flash point 73.5 °C
Application
Ethyl acetoacetate can be used as a reactant to synthesize:
It can be also utilized as a reactant in the transesterification and asymmetric hydrogenation reactions to produce valuable products.
- 7-hydroxycoumarin derivatives via Pechmann condensation reaction with 1,3-dihydroxybenzene in the presence of acid catalysts.
- 2,6-disubstituted piperidine alkaloid, (−)-pinidinone via stereoselective α-aminoallylation followed by Grubbs′ olefin cross-metathesis reaction.
- Michael addition products via Michael addition reaction with chalcones and azachalcones in the presence of a base catalyst.
- α, β-unsaturated carbonyl compounds via Knoevenagel condensation reaction with glyceraldehyde acetonide in the presence of a base catalyst.
It can be also utilized as a reactant in the transesterification and asymmetric hydrogenation reactions to produce valuable products.
Analysis Note
Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.028 - 1.030
Identity (IR): passes test
Density (d 20 °C/ 4 °C): 1.028 - 1.030
Identity (IR): passes test
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
164.3 °F - closed cup
flash_point_c
73.5 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service