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8.12382

Sigma-Aldrich

Titanium(IV) chloride

for synthesis

Synonym(s):

Titanium(IV) chloride, Titanium tetrachloride

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About This Item

Empirical Formula (Hill Notation):
Cl4Ti
CAS Number:
7550-45-0
Molecular Weight:
189.68
MDL number:
MFCD00011267
UNSPSC Code:
12352302
EC Index Number:
231-441-9
NACRES:
NA.22
grade:
for synthesis
synthesis grade
form:
liquid

grade

for synthesis
synthesis grade

Quality Level

200

vapor pressure

12 hPa ( 20 °C)

form

liquid

potency

3160 mg/kg LD50, skin (Rabbit)

bp

136 °C/1013 hPa

mp

-24 °C

density

1.728 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

[Ti+4].[Cl-].[Cl-].[Cl-].[Cl-]

Application

Titanium(IV) chloride can be used as a Lewis acid catalyst:
  • In the ortho acylation of aryl alcohols to synthesize corresponding ortho C-acylated products.
  • To synthesize various chlorinated compounds via Baylis−Hillman reaction reactions of aryl aldehydes with methyl vinyl ketone in the presence of Lewis base.
  • To prepare 3,4-dihydropyrimidin-2(1H)-ones and thiones by Biginelli condensation reaction of aldehyde, 1,3-dicarbonyl compound, and urea or thiourea.
  • In the hydrodefluorination reaction in the presence of triethylsilane as the reducing agent.

Analysis Note

Assay (argentometric): ≥ 97.0 %
Identity (ICP-OES): passes test

pictograms

CorrosionSkull and crossbones
GHS05,GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH014

Storage Class

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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