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Key Documents

8.52220

Sigma-Aldrich

Fmoc-Asp-OBzl

Novabiochem®

Synonym(s):

Fmoc-Asp-OBzl, N-α-Fmoc-L-aspartic acid α-benzyl ester

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About This Item

Empirical Formula (Hill Notation):
C26H23NO6
CAS Number:
86060-83-5
Molecular Weight:
445.46
MDL number:
MFCD00198201
UNSPSC Code:
12352209
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

200

product line

Novabiochem®

assay

≥90.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

carboxylic acid

storage temp.

2-30°C

SMILES string

N([C@@H](CC(=O)O)C(=O)OCc4ccccc4)C(=O)OCC1c2c(cccc2)c3c1cccc3

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This Item
5171278.0352513259
Dimethyl carbonate ReagentPlus®, 99%

D152927

Dimethyl carbonate

Dimethyl carbonate anhydrous, ≥99%

517127

Dimethyl carbonate

Dimethyl carbonate for synthesis

8.03525

Dimethyl carbonate

Dimethyl carbonate analytical standard

13259

Dimethyl carbonate

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

assay

99%

assay

≥99%

assay

≥99.0% (GC)

assay

≥99.0% (GC)

form

liquid

form

liquid

form

liquid

form

-

bp

90 °C (lit.)

bp

90 °C (lit.)

bp

90 °C/1016 hPa

bp

90 °C (lit.)

density

1.069 g/mL at 25 °C (lit.)

density

1.069 g/mL at 25 °C (lit.)

density

1.07 g/cm3 at 20 °C

density

1.069 g/mL at 25 °C (lit.)

mp

2-4 °C (lit.)

mp

2-4 °C (lit.)

mp

0.5-4.7 °C

mp

2-4 °C (lit.)

General description

Building block for introduction of aspartic acid bearing TFA-labile benzyl ester protection. Benzyl group is removed by hydrogenation over Pd/C or with strong acids such as TFMSA.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1272

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Direct synthesis of dimethyl carbonate from carbon dioxide and methanol catalyzed by base.
    Fang S and Fujimoto K.
    Applied Catalysis A: General, 142(1), L1-L3 (1996)
    Thermodynamic Properties of Dimethyl Carbonatea).
    Zhou Y, et al.
    Journal of Physical and Chemical Reference Data, 40(4), 043106-043106 (2011)
    Jana Engeldinger et al.
    Physical chemistry chemical physics : PCCP, 14(7), 2183-2191 (2011-11-18)
    The simultaneous combination of steady state isotopic transient kinetic analysis (SSITKA) with diffuse reflectance Fourier transform spectroscopy (DRIFTS) and mass spectrometric (MS) analysis was applied to study the oxidative carbonylation of methanol (MeOH) to dimethyl carbonate (DMC) on a CuY
    Catalysis in the production and reactions of dimethyl carbonate, an environmentally benign building block.
    Ono Y.
    Applied Catalysis A: General, 155(2), 133-166 (1997)
    Liping Zhang et al.
    Bioresource technology, 101(21), 8144-8150 (2010-07-02)
    The transesterification of palm oil with dimethyl carbonate (DMC) for preparing biodiesel has been studied in solvent-free system at the catalysis of potassium hydroxide (KOH) as heterogeneous catalyst. Fatty acid methyl esters (FAMEs) were analyzed by GC with internal standard
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