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IF011

Sigma-Aldrich

Interferon-β Protein, Recombinant mouse

Interferon-β Protein, Recombinant mouse.

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.77

Pricing and availability is not currently available.

biological source

mouse

Quality Level

recombinant

expressed in E. coli

assay

≥95%

form

liquid

manufacturer/tradename

Chemicon®

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

shipped in

dry ice

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This Item
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material

PVDF membrane, white filter, plain filter

material

PVDF membrane, plain filter, white filter

material

PVDF membrane, plain filter, white filter

material

PVDF membrane, plain filter, white filter

pore size

0.45 μm

pore size

0.45 μm

pore size

0.20 μm pore size

pore size

0.45 μm pore size

detection method

chemiluminescent, radioactive, colorimetric

detection method

chemiluminescent, colorimetric, fluorometric, radioactive

detection method

chemiluminescent, colorimetric, radioactive

detection method

chemiluminescent, colorimetric, radioactive

capacity

160 μg/cm2 adsorption capacity(Insulin), 294 μg/cm2 adsorption capacity(Goat IgG), 215 μg/cm2 adsorption capacity(BSA)

capacity

155 μg/cm2 adsorption capacity(Insulin), 205 μg/cm2 adsorption capacity(BSA), 300 μg/cm2 adsorption capacity(Goat IgG)

capacity

262 μg/cm2 adsorption capacity(Insulin), 340 μg/cm2 adsorption capacity(BSA), 448 μg/cm2 adsorption capacity(Goat IgG)

capacity

-

technique(s)

western blot: suitable

technique(s)

western blot: suitable

technique(s)

dot blot: suitable, western blot: suitable

technique(s)

western blot: suitable

feature

hydrophobic

feature

hydrophobic

feature

hydrophobic

feature

easily wetted with water

General description

Purified Recombinant Mouse Interferon β (IFNbeta)

Unit Definition

Specific Activity: The units are determined with respect to the international reference standard for mouse interferon beta (IFNbeta) provided by the National Institutes of Health.Unit of activity measured on mouse L929 cells with encephalomyocarditis virus (EMCV).

Analysis Note

Specific Activity: Determined by assaying inhibition of virus-induced cytopathic effect.In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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    Shawn M Freed et al.
    FEBS letters, 595(21), 2665-2674 (2021-10-01)
    Toll-like receptor 3 (TLR3) recognizes viral double-stranded RNA (or the synthetic dsRNA analog poly I:C) and induces a signal transduction pathway that results in activation of transcription factors that induce expression of antiviral genes including type I interferon (IFN-I). Secreted
    Paulino Barragán-Iglesias et al.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(18), 3517-3532 (2020-04-05)
    One of the first signs of viral infection is body-wide aches and pain. Although this type of pain usually subsides, at the extreme, viral infections can induce painful neuropathies that can last for decades. Neither of these types of pain

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