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MAB4337

Sigma-Aldrich

Anti-UTF-1 Antibody, clone 5G10.2

clone 5G10.2, Chemicon®, from mouse

Synonym(s):

Anti-AI505934

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

5G10.2, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

input

sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)
sample type: human embryonic stem cell(s)

isotype

IgG1κ

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This Item
SAB2501646MABC1701FCMAB113A4
Anti-UTF-1 Antibody, clone 5G10.2 clone 5G10.2, Chemicon®, from mouse

MAB4337

Anti-UTF-1 Antibody, clone 5G10.2

Anti-UTF1 antibody produced in goat affinity isolated antibody, buffered aqueous solution

SAB2501646

Anti-UTF1 antibody produced in goat

Anti-PDGF-AA Antibody, clone 5C10.8

MABC1701

Anti-PDGF-AA Antibody, clone 5C10.8

Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor™ 488 conjugate clone 10H11.2, from mouse, ALEXA FLUOR™ 488

FCMAB113A4

Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor™ 488 conjugate

antibody form

purified antibody

antibody form

affinity isolated antibody

antibody form

purified antibody

antibody form

purified antibody

Gene Information

human ... UTF1(8433)

Gene Information

human ... UTF1(8433)

Gene Information

human ... PDGFA(5154)

Gene Information

human ... POU5F1(5460)

biological source

mouse

biological source

goat

biological source

mouse

biological source

mouse

clone

5G10.2, monoclonal

clone

polyclonal

clone

5C10.8, monoclonal

clone

10H11.2, monoclonal

isotype

IgG1κ

isotype

-

isotype

IgG2bκ

isotype

IgG1

General description

UTF1 is a transcription factor that was originally identified due to its expression in Embryonic Stem (ES) cells, Embryonic Carcinoma (EC) cells, and germ line tissues. Expression was not found in adult tissues. It was thought at the time that UTF1 might play an important role in early molecular events of embryogenesis. Subsequent studies have shown that UTF1 is a target of the Oct-4 / Sox-2 complex, a key determinant of pluripotency in stem cells

Immunogen

Recombinant GST Fusion protein, human UTF-1

Application

Anti-UTF-1 Antibody, clone 5G10.2 detects level of UTF-1 & has been published & validated for use in ELISA, WB & IC.

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

    • Certificates of Analysis (COA)

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    Xiao-Ling Wu et al.
    Carcinogenesis, 34(7), 1660-1668 (2013-03-29)
    Undifferentiated embryonic cell transcription factor-1 (UTF1) is an important transcription factor during development, which plays critical roles in cell fate determination. However, its expression and function in somatic tissues remain unclear. Here, we investigated the expression pattern of the UTF1
    M Nishimoto et al.
    Molecular and cellular biology, 19(8), 5453-5465 (1999-07-20)
    UTF1 is a transcriptional coactivator which has recently been isolated and found to be expressed mainly in pluripotent embryonic stem (ES) cells (A. Okuda, A. Fukushima, M. Nishimoto, et al., EMBO J. 17:2019-2032, 1998). To gain insight into the regulatory
    Functional characterization of single-nucleotide polymorphisms in the human undifferentiated embryonic-cell transcription factor 1 gene.
    Rajkumar P Thummer,Loes J Drenth-Diephuis,Karen E Carney,Bart J L Eggen
    Dna and Cell Biology null
    Characterization of human UTF1, a chromatin-associated protein with repressor activity expressed in pluripotent cells.
    Susanne M Kooistra,Rajkumar P Thummer,Bart J L Eggen
    Stem Cell Research null
    Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms.
    Kristensen, DM; Nielsen, JE; Skakkebaek, NE; Graem, N; Jacobsen, GK; Rajpert-De Meyts, E; Leffers, H
    Human Reproduction null
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