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Key Documents

MAB80122

Sigma-Aldrich

Anti-Human Metapneumovirus Antibody, clone 67

clone 67, Chemicon®, from mouse

Synonym(s):

hMPV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.42
Pricing and availability is not currently available.

biological source

mouse

Quality Level

300

antibody form

purified antibody

antibody product type

primary antibodies

clone

67, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable

isotype

IgG1

shipped in

wet ice

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Emodin from Frangula bark, ≥90% (HPLC)

E7881

Emodin

Emodin A cell-permeable, reversible, substrate competitive and potent p56lck tyrosine kinase inhibitor (IC₅₀ = 18.5 µM).

324694

Emodin

Emodin analytical standard

30269

Emodin

Emodin phyproof® Reference Substance

PHL89191

Emodin

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥97.0% (HPLC)

assay

≥90.0% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

solubility

DMSO: soluble, ethanol: soluble, aqueous base: soluble

solubility

DMSO: 1 mg/mL, aqueous base: soluble, ethanol: soluble

solubility

-

solubility

-

biological source

Frangula bark

biological source

-

biological source

-

biological source

-

Gene Information

human ... CSNK2A1(1457), CSNK2B(1460), ELA2(1991), NFKB1(4790), NKAP(79576), NKRF(55922)

Gene Information

-

Gene Information

-

Gene Information

-

General description

Human metapneumovirus (hMPV) is a member of the pneumovirinae subfamily of paramyxoviruses, first described in 2001 from pediatric respiratory specimens in the Netherlands. It is an enveloped pleomorphic virus with a single negative-strand RNA genome. Two major serotypes, A and B, have been described. Several studies identified hMPV in specimens worldwide, and estimated that by age 5 years 70% of children have developed antibodies to hMPV.

Specificity

Specific to the fusion protein. Reactive with all sub-types; A1, A2, B1, B2.

Application

Detect Human Metapneumovirus using this Anti-Human Metapneumovirus Antibody, clone 67 validated for use in ELISA, FC & IF.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Liquid in 0.02M PB with 0.25M NaCl, pH 7.6. Contains 0.1% sodium azide.

Storage and Stability

Store at 2° to 8°C for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

    • Certificates of Analysis (COA)

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    Charles J Russell et al.
    Virology, 509, 60-66 (2017-06-13)
    Human metapneumovirus (hMPV) infections pose a serious health risk to young children, particularly in cases of premature birth. No licensed vaccine exists and there is no standard treatment for hMPV infections apart from supportive hospital care. We describe the production
    Analysis of the genomic sequence of a human metapneumovirus
    van den Hoogen, Bernadette G, et al
    Virology, 295, 119-132 (2002)
    Human metapneumovirus associated with respiratory tract infections in a 3-year study of nasal swabs from infants in Italy.
    Maggi, Fabrizio, et al.
    Journal of Clinical Microbiology, 41, 2987-2991 (2003)

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