Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

OP133

Sigma-Aldrich

Anti-IKKα Mouse mAb (14A231)

liquid, clone 14A231, Calbiochem®

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

mouse

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

14A231, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

monkey, human, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
OP115ST1521CP45
Anti-IKKα Mouse mAb (14A231) liquid, clone 14A231, Calbiochem®

OP133

Anti-IKKα Mouse mAb (14A231)

Anti-MDM2 (Ab-2) Mouse mAb (2A10) liquid, clone 2A10, Calbiochem®

OP115

Anti-MDM2 (Ab-2) Mouse mAb (2A10)

Anti-ULK1 Mouse mAb (2H8) liquid, clone 2H8, Calbiochem®

ST1521

Anti-ULK1 Mouse mAb (2H8)

Anti-Clathrin Heavy Chain Mouse mAb (X22) liquid, clone X22, Calbiochem®

CP45

Anti-Clathrin Heavy Chain Mouse mAb (X22)

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

Gene Information

human ... CHUK(1147)

Gene Information

human ... MDM2(4193)

Gene Information

human ... ULK1(8408)

Gene Information

human ... CLTCL1(8218)

clone

14A231, monoclonal

clone

2A10, monoclonal

clone

2H8, monoclonal

clone

X22, monoclonal

species reactivity

monkey, human, mouse

species reactivity

human

species reactivity

human

species reactivity

bovine, mouse, rat, human

antibody form

affinity isolated antibody

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

General description

Immunoaffinity purified mouse monoclonal antibody. Recognizes the ~85 kDa IKKα protein.
Recognizes the ~85 kDa IKKα protein in Daudi cells.
This Anti-IKKα Mouse mAb (14A231) is validated for use in Immunoblotting for the detection of IKKα.

Immunogen

Human
a recombinant protein consisting of full-length human IKKα/IKK1 fused to a His•Tag sequence

Application


Immunoblotting (1-2 g/ml, chemiluminescence)

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS, 0.2% gelatin, pH 7.4.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

Positive Control
Daudi cells

Other Notes

Antibody should be titrated for optimal results in individual systems.
Zandi, E., et al. 1998 Science281, 1360.
Didonato, J.A., et al. 1997 Nature388, 548.
Lee, F.S., et al. 1997 Cell88, 213.
Mercurio, F., et al. 1997 Science278, 860.
Regnier, C.H., et al. M. 1997 Cell90, 373.
Verma, I. and Stevenson, J.K. 1997 Proc. Nat. Acad. Sci. USA94, 11758.
Verma, I.M., et al. 1995 Genes. Dev.9, 2723.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

    • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Jonathan M Starkey et al.
    Diabetes, 55(5), 1252-1259 (2006-04-29)
    Evidence of diabetes-induced nuclear factor-kappaB (NF-kappaB) activation has been provided with DNA binding assays or nuclear localization with immunohistochemistry, but few studies have explored mechanisms involved. We examined effects of diabetes on proteins comprising NF-kappaB canonical and noncanonical activation pathways
    Carlota Colomer et al.
    Molecular cell, 75(4), 669-682 (2019-07-16)
    Phosphorylated IKKα(p45) is a nuclear active form of the IKKα kinase that is induced by the MAP kinases BRAF and TAK1 and promotes tumor growth independent of canonical NF-κB signaling. Insights into the sources of IKKα(p45) activation and its downstream

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service