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11685929001

Sigma-Aldrich

Guanidine thiocyanate

Synonym(s):

Guanidine thiocyanate, Guanidinium rhodanide, Guanidinium thiocyanate

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About This Item

Linear Formula:
NH2C(=NH)NH2 · HSCN
CAS Number:
593-84-0
Molecular Weight:
118.16
Beilstein/REAXYS Number:
3563461
MDL number:
MFCD00013027
UNSPSC Code:
12352200
PubChem Substance ID:
329749530
Pricing and availability is not currently available.

form

solid

mol wt

118.16

packaging

pkg of 500 g

manufacturer/tradename

Roche

mp

120-122 °C (lit.)

absorption

≤0.10 at 300 and 410 nm in water at 6 M

shipped in

ambient

storage temp.

20-25°C

SMILES string

SC#N.NC(N)=N

InChI

1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H

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manufacturer/tradename

Supelco

manufacturer/tradename

Supelco

manufacturer/tradename

-

manufacturer/tradename

-

packaging

pkg of 50 pkg

packaging

pkg of 50 ea

packaging

pkg of 250 ea

packaging

pkg of 50 ea

diam.

11 mm ( 7/16 in.)

diam.

12.5 mm ( 1/2 in.)

diam.

10 mm ( 13/32 in.)

diam.

11 mm ( 7/16 in.)

General description

Guanidine thiocyanate is chaotropic salts which lyse cells and along with nuclease binding matrix it is also seen to inhibit nuclease activity during extraction of DNA. It works as a strong RNase inhibitor in extraction buffers.

Application

Chaotropic agent and strong denaturant; solubilizes cells.
Suitable as denaturing agent for proteins. Guanidine thiocyanate is a stronger denaturant than guanidine hydrochloride.
Suitable as denaturing agent for proteins. Guanidine thiocyanate is a stronger denaturant than guanidine hydrochloride.[1]

Specifications

Absorbance: A300 and A410 ≤0.10 (6 M in H2O) each
Formula: CH5N3 x HSCN

Physical form

Crystals

Other Notes

For life science research only. Not for use in diagnostic procedures.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 Inhalation - Eye Dam. 1 - Skin Corr. 1C

supp_hazards

EUH032,EUH071

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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    Certificates of Analysis (COA)

    Lot/Batch Number
    23E0156549
    22G1856095
    23C1556850
    94021520
    940196

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