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09-1500

Sigma-Aldrich

Ethylenediaminetetraacetic acid iron(III) sodium salt

SAJ special grade, ≥95.0%

Synonym(s):

EDTA iron(III) sodium salt, Edathamil, Komplexon™ II

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About This Item

Linear Formula:
C10H12N2NaFeO8
CAS Number:
15708-41-5
Molecular Weight:
367.05
EC Number:
239-802-2
MDL number:
MFCD00078215
UNSPSC Code:
12352116
PubChem Substance ID:
329748704
Pricing and availability is not currently available.

grade

SAJ special grade

assay

≥95.0%

form

crystalline

availability

available only in Japan

mp

80 °C

solubility

water: 72 g/L at 25 °C

shipped in

ambient

SMILES string

[Na+].[Fe+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.Fe.Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;+3;+1/p-4

InChI key

MKWYFZFMAMBPQK-UHFFFAOYSA-J

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assay

≥93% (HPLC)

assay

≥96% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

film

form

solid

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 10 mg/mL

solubility

DMSO: 50 mg/mL

solubility

DMSO: 50 mg/mL

solubility

DMSO: 100 mg/mL

Application

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors. Iron-EDTA enhances damage due to reactive oxygen species, such as depletion of reduced glutathione, formation of methemoglobin, and lipid peroxidation.

Legal Information

Komplexon is a trademark of CU Chemie Uetikon AG

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
U1140
U9755
U9547
U8444
U2325

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Suying Chang et al.
Food and nutrition bulletin, 33(2), 111-116 (2012-08-23)
Ferric sodium ethylenediaminetetraacetate (NaFeEDTA) enhances iron absorption in the presence of phytate. However, the amount of NaFeEDTA that would have to be added to a complementary food to provide the necessary intake of iron for an infant or young child
Abdul-Razak Abizari et al.
The Journal of nutrition, 142(11), 1950-1955 (2012-09-20)
Limited data exist on iron absorption from NaFeEDTA and FeSO(4) in legume-based flours. The current study compared iron absorption from NaFeEDTA and FeSO(4) as fortificants within and between red and white varieties of cowpea with different concentrations of polyphenols (PP)
Abdul-Razak Abizari et al.
The Journal of nutrition, 142(10), 1836-1842 (2012-08-24)
Cowpeas, like other legumes, contain high amounts of native iron but are rich in phytic acid (PA) and polyphenols (PP) that inhibit iron absorption. NaFeEDTA may overcome the combined inhibitory effect of PA and PP. Our objective was to test
Kwan-Young Jung et al.
Biochemistry, 50(28), 6273-6279 (2011-06-24)
Oxidation of the C5'-position of DNA results in direct strand scission. The 3'-fragments produced contain DNA lesions at their 5'-termini. The major DNA lesion contains an aldehyde at its C5'-position, but its nucleobase is unmodified. Excision of the lesion formed
Klaus Schümann et al.
Food and nutrition bulletin, 33(2), 128-136 (2012-08-23)
Oral iron supplementation with ferrous sulfate (FeSO₄) at dosage levels suggested by the international guidelines poses a safety hazard to young children with malaria. Exposure to loosely bound iron in the circulation has been advanced as a potential factor. To
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