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03951

Sigma-Aldrich

N-Ethylformamide

≥99.0% (GC)

Synonym(s):

N-Formylethylamine

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About This Item

Linear Formula:
HCONHC2H5
CAS Number:
627-45-2
Molecular Weight:
73.09
Beilstein/REAXYS Number:
1737860
EC Number:
211-001-2
MDL number:
MFCD00042672
UNSPSC Code:
12352100
PubChem Substance ID:
329747846
NACRES:
NA.22

Quality Level

100
500

assay

≥99.0% (GC)

form

liquid

refractive index

n20/D 1.432

bp

202-204 °C

density

0.950 g/mL at 20 °C (lit.)

functional group

amide

SMILES string

CCNC=O

InChI

1S/C3H7NO/c1-2-4-3-5/h3H,2H2,1H3,(H,4,5)

InChI key

KERBAAIBDHEFDD-UHFFFAOYSA-N

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Related Categories

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC8787
BCCC2603
BCBX0975

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P Kestell et al.
The Journal of pharmacology and experimental therapeutics, 240(1), 265-270 (1987-01-01)
The hepatotoxicity and metabolism of the following close analogs of the hepatotoxic antitumor agent N-methylformamide (NMF) were investigated in CBA/CA mice: N-ethylformamide (NEF), dimethylformamide (DMF), formamide and N-methylacetamide (NMA). Apart from NMF only NEF was potently hepatotoxic as measured by
S P Langdon et al.
Toxicology, 43(3), 239-249 (1987-03-01)
The induction of terminal differentiation in tumour cells represents a possible therapeutic strategy for treating cancer. The alkylformamides are 1 group of experimental compounds which have been shown to induce terminal differentiation in human HL-60 leukemia and murine Friend erythroleukemia
M R Del Carratore et al.
Environmental and molecular mutagenesis, 36(2), 97-104 (2000-10-03)
A cDNA coding for rat cytochrome P450 2E1 was cloned into the multicopy vector pYeDP60 and expressed in haploid RSY6 and diploid RS112 yeast strains of Saccharomyces cerevisiae under control of the GAL10-CYC1 promoter. Spectral and catalytic properties of the
Gil-Soo Han et al.
The Journal of biological chemistry, 283(29), 20443-20453 (2008-05-07)
The Saccharomyces cerevisiae DGK1 gene encodes a diacylglycerol kinase enzyme that catalyzes the formation of phosphatidate from diacylglycerol. Unlike the diacylglycerol kinases from bacteria, plants, and animals, the yeast enzyme utilizes CTP, instead of ATP, as the phosphate donor in
H Cross et al.
Chemical research in toxicology, 3(4), 357-362 (1990-07-01)
Hepatotoxic formamides such as N-methylformamide (NMF) and N,N-dimethylformamide (DMF) are metabolized in vivo to N-acetyl-S-(N-methylcarbamoyl)cysteine via oxidation at the formyl carbon, which yields a reactive intermediate. The hypothesis was tested that this biotransformation route can be studied in vitro with
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