17755

4-Borono-L-phenylalanine

≥95.0% (HPLC)

• Synonym(s): 4-Dihydroxyboryl-L-phenylalanine, L-BPA
• Empirical Formula (Hill Notation): C₉H₁₂BNO₄
• CAS Number: 76410-58-7
• Molecular Weight: 209.01
• Beilstein/REAXYS Number: 4458616
• MDL number: MFCD01075172
• UNSPSC Code: 12352209
• PubChem Substance ID: 329751559
• NACRES: NA.21

Properties

• Quality Level: 100
• assay: ≥95.0% (HPLC)
• storage temp.: 2-8°C
• SMILES string: N[C@@H](Cc1ccc(cc1)B(O)O)C(O)=O
• InChI: 1S/C9H12BNO4/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15/h1-4,8,14-15H,5,11H2,(H,12,13)/t8-/m0/s1
• InChI key: NFIVJOSXJDORSP-QMMMGPOBSA-N

Description

Application

4-Borono-L-phenylalanine can be used as a building block in solid-phase peptide synthesis. It can also be used to synthesize substituted triazine derivatives as potential tryptophan hydroxylase inhibitors via Suzuki cross-coupling reaction using palladium as a catalyst.

Other Notes

Tyrosine analogue; employed for treatment of melanom cells by boron neutron capture therapy

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves