49702
Carnosol
analytical standard
Synonym(s):
Picrosalvin
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About This Item
Empirical Formula (Hill Notation):
C20H26O4
CAS Number:
Molecular Weight:
330.42
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
biological source
Rosemarinus officinalis L. leaves
Quality Level
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
−20°C
SMILES string
CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O
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General description
Carnosol is a naturally occurring phyto polyphenolor phenolic diterpene, found in rosemary, which can show a broad spectrum of applications as a an antioxidant, anticancer agent and anti-inflammatory agent.
Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis.The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.Addition of rosemary extracts to the diet as a 1% supplement by weight was also found to decrease the frequency of DMBA-DNA adducts.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
A phenolic diterpene with antioxidant and anticarcinogenic activities.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
This compound is commonly found in plants of the genus: salvia
signalword
Warning
hcodes
pcodes
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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