69400

6-Methyl-2-thiouracil

purum, ≥98.0% S basis (elemental analysis)

• Synonym(s): Basethyrin, Methiocil, Thiothymin, 4-Hydroxy-2-mercapto 6-methylpyrimidine, MZU
• Empirical Formula (Hill Notation): C₅H₆N₂OS
• CAS Number: 56-04-2
• Molecular Weight: 142.18
• Beilstein/REAXYS Number: 115648
• EC Number: 200-252-3
• MDL number: MFCD00006040
• UNSPSC Code: 12352100
• PubChem Substance ID: 329761639
• NACRES: NA.22

Properties

• grade: purum
• Quality Level: 300
• assay: ≥98.0% S basis (elemental analysis)
• form: crystals
• mp: ~330 °C (dec.) (lit.)
• SMILES string: CC1=CC(=O)NC(=S)N1
• InChI: 1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)
• InChI key: HWGBHCRJGXAGEU-UHFFFAOYSA-N

Description

General description

6-Methyl-2-thiouracil possesses antithyroid activity.

Application

6-Methyl-2-thiouracil can be used in:

• Synthesis of luminescent gold(I) thiouracilate complexes as emissive materials.
• Synthesis of uracil-containing histone deacetylase inhibitors.
• Synthesis of S-dihydro-alkylthio-benzyl-oxopyrimidines (S-DABOs) based anti-HIV agents.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges