71230

Thimerosal

97.0-101.0% (on dried substance, T)

• Synonym(s): 2-(Ethylmercuriomercapto)benzoic acid sodium salt, Ethylmercurithiosalicylic acid sodium salt, Mercury-([o-carboxyphenyl]thio)ethyl sodium salt, Sodium ethylmercurithiosalicylate
• Linear Formula: 2-(C₂H₅HgS)C₆H₄CO₂Na
• CAS Number: 54-64-8
• Molecular Weight: 404.81
• Beilstein/REAXYS Number: 8169555
• EC Number: 200-210-4
• MDL number: MFCD00013062
• UNSPSC Code: 51473202
• PubChem Substance ID: 329763125
• NACRES: NA.21

Properties

• Quality Level: 200
• assay: 97.0-101.0% (on dried substance, T)
• form: powder
• mp: 234-237 °C (dec.) (lit.)
• mode of action: enzyme | inhibits
• SMILES string: [Na+].CC[Hg]Sc1ccccc1C([O-])=O
• InChI: 1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
• InChI key: RTKIYNMVFMVABJ-UHFFFAOYSA-L

Description

Biochem/physiol Actions

Thimerosal is a sulfhydryl (thiol) oxidizing reagent capable of inhibiting a wide range of sulfhydryl-dependent enzymes and proteins such as PI3-kinase-dependent methionine synthase, glutamate transport receptors, and Na⁺+K⁺ dependent ATPases.

Analysis Note

Solubility (EP/BP) Freely soluble in water, sparingly soluble or soluble in ethanol (96%), practically insoluble in ether and methylene cholride.

Other Notes

As part of the corporation global plan to support the Minamata Convention eliminating mercury-containing compounds, as of January 2021 customers will be required to provide an End-Use Declaration. Sales of thimerosal will be restricted for approved applications only.

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Safety Information

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H300 + H310 + H330,H373,H410
• pcodes: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
• target_organs: Kidney
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges