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93598

Supelco

Itaconic acid

analytical standard

Synonym(s):

Methylenesuccinic acid

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About This Item

Linear Formula:
HO2CCH2C(=CH2)CO2H
CAS Number:
97-65-4
Molecular Weight:
130.10
Beilstein/REAXYS Number:
1759501
EC Number:
202-599-6
MDL number:
MFCD00004260
UNSPSC Code:
85151701
PubChem Substance ID:
329770255
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

100

assay

≥96.0% (GC)

autoignition temp.

1472 °F

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤0.5% water

mp

165-168 °C (lit.)

density

1.573 g/mL at 25 °C (lit.)

format

neat

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891434989345629
Itaconic acid analytical standard

93598

Itaconic acid

Adipic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

89143

Adipic acid

Succinic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

49893

Succinic acid

Erucic acid analytical standard

45629

Erucic acid

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

grade

analytical standard

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

grade

analytical standard

format

neat

format

neat

format

neat

format

neat

assay

≥96.0% (GC)

assay

-

assay

-

assay

≥99.0% (GC)

autoignition temp.

1472 °F

autoignition temp.

788 °F

autoignition temp.

-

autoignition temp.

-

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

General description

Itaconic acid, an unsaturated dicarbonic organic acid,[1] is a metabolic product of Aspergillus itaconicus.[2]
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF4378
BCBZ8506
BCBS8239V

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Sambamurthy K.
Pharmaceutical Biotechnology, 56(3-4), 289-295 (2006)
T Willke et al.
Applied microbiology and biotechnology, 56(3-4), 289-295 (2001-09-11)
Itaconic acid (IA) is an unsaturated dicarbonic organic acid. It can easily be incorporated into polymers and may serve as a substitute for petrochemical-based acrylic or methacrylic acid. It is used at 1-5% as a co-monomer in resins and also
Mitsuyasu Okabe et al.
Applied microbiology and biotechnology, 84(4), 597-606 (2009-07-25)
More than 80,000 tons of itaconic acid (IA) is produced worldwide each year and is sold at a price of around US$ 2/kg. The IA production yield from sugar is higher than 80 g/l. The widespread use of IA in
Jahminy Sasikaran et al.
Nature chemical biology, 10(5), 371-377 (2014-03-25)
Itaconate (methylenesuccinate) was recently identified as a mammalian metabolite whose production is substantially induced during macrophage activation. This compound is a potent inhibitor of isocitrate lyase, a key enzyme of the glyoxylate cycle, which is a pathway required for the
Metabolism: pathogens love the poison.
Stéphane Ménage et al.
Nature chemical biology, 10(5), 326-327 (2014-04-20)
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