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M2649

Sigma-Aldrich

Melanin from Sepia officinalis

99% purity (TLC), powder

Synonym(s):

Melanin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.47

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Product Name

Melanin from Sepia officinalis, 99% (TLC)

Quality Level

assay

99% (TLC)

form

powder

solubility

hydrogen peroxide: 1 mg/mL, dark brown

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[nH]1c2c3c(c4c5c([nH]c4)c([c]([c](c5c3c1)=O)=O)C)[c]([c](c2C)=O)=O

InChI

1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3

InChI key

XUMBMVFBXHLACL-UHFFFAOYSA-N

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This Item
D6319PLA0262WH0083594M1
antibody form

serum

antibody form

affinity isolated antibody

antibody form

affinity purified immunoglobulin

antibody form

purified immunoglobulin

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

species reactivity

mouse, human

species reactivity

rat, mouse, human

species reactivity

human

species reactivity

human

Gene Information

human ... DCP2(167227)

Gene Information

human ... DCP2(167227)
mouse ... Dcp2(20640)
rat ... Dcp2(291604)

Gene Information

rabbit ... Dcp2(167227)

Gene Information

human ... NUDT12(83594)

clone

polyclonal

clone

polyclonal

clone

-

clone

3F7, monoclonal

UniProt accession no.

Q8IU60

UniProt accession no.

Q8IU60

UniProt accession no.

Q8IU60

UniProt accession no.

Q9BQG2

General description

Melanin is a ubiquitous and prominent pigment responsible for color of skin, hair and eyes. Melanin is classified into eumelanin and pheomelanin. Eumelanin is black to dark brown pigment and is present in black hair and retina of the eye. Pheomelanin is yellow to reddish brown pigment present is red hair and red feathers.[1] Melanins are high molecular weight pigments synthesized from phenolic or indolic precursors and is widely present in animals, plants and microorganisms.[2]

Application

Melanin from Sepia officinalis has been used:
  • as a natural pigment for Raman spectroscopy measurements[1]
  • in competitive enzyme linked immunosorbent assay (ELISA) for the characterization of phage antibodies[2]
  • as an external standard for spectrophotometrically determining the melanin production in B16F10 cells[3]

Biochem/physiol Actions

Melanin scavenges active chemical species and acts as a sunscreen.[1]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Articles

Glycosyltransferases were initially considered to be specific for a single glycosyl donor and acceptor, which led to the one enzyme-one linkage concept. Subsequent observations have refuted the theory of absolute enzymatic specificity by describing the transfer of analogs of some nucleoside mono- or diphosphate sugar donors.

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