M8010

N,N′-Dimethyl-9,9′-biacridinium dinitrate

Powder

• Synonym(s): 9,9′-Bis(N-methylacridinium nitrate), Lucigenin
• Empirical Formula (Hill Notation): C₂₈H₂₂N₄O₆
• CAS Number: 2315-97-1
• Molecular Weight: 510.50
• Beilstein/REAXYS Number: 3901768
• EC Number: 219-023-4
• MDL number: MFCD00011925
• UNSPSC Code: 12171500
• PubChem Substance ID: 24897210
• NACRES: NA.47

Properties

• Product Name: N,N′-Dimethyl-9,9′-biacridinium dinitrate, used as chemiluminescent reagent
• Quality Level: 100
• form: powder
• mp: 245-250 °C
• solubility: acetic acid: 10 mg/mL
• fluorescence: λ_ex 319 nm; λ_em 384 nm (pH 9.0); λ_ex 360 nm; λ_em 449 nm (Reaction product); λ_ex 368 nm; λ_em 505 nm in H₂O
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [O-][N+]([O-])=O.[O-][N+]([O-])=O.C[n+]1c2ccccc2c(-c3c4ccccc4[n+](C)c5ccccc35)c6ccccc16
• InChI: 1S/C28H22N2.2NO3/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28;2*2-1(3)4/h3-18H,1-2H3;;/q+2;2*-1

Description

Application

N,N′-Dimethyl-9,9′-biacridinium dinitrate has been used in chemiluminescence assay to measure reactive oxygen species production[1][2] and superoxide production.[3][4][5]

Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen; it is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)