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Key Documents

PHR1352

Supelco

NMP

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

1-Methyl-2-pyrrolidinone, 1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP

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About This Item

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
Molecular Weight:
99.13
Beilstein/REAXYS Number:
106420
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

Pricing and availability is not currently available.

Product Name

N-Methylpyrrolidone, Pharmaceutical Secondary Standard; Certified Reference Material

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1437202

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

CofA

current certificate can be downloaded

autoignition temp.

518 °F

expl. lim.

9.5 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

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1 of 4

This Item
1601703787691.02497
application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

application(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

GC-HS: suitable

format

neat

format

neat

format

neat

format

-

Quality Level

300

Quality Level

-

Quality Level

100

Quality Level

100

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

analytical standard

grade

-

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

2-30°C

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

N-Methylpyrrolidone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.[1][2]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB8250 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Analyte

Description

    1-Methyl-2-pyrrolidinone

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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