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RTC000087

Supelco

Ethyl Acetate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Ethyl acetate, EtOAc

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About This Item

Linear Formula:
CH3COOC2H5
CAS Number:
141-78-6
Molecular Weight:
88.11
Beilstein/REAXYS Number:
506104
MDL number:
MFCD00009171
UNSPSC Code:
41116107
Pricing and availability is not currently available.

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to USP 1265402

vapor density

3 (20 °C, vs air)

vapor pressure

73 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

801 °F

expl. lim.

2.2-11.5 %, 38 °F

packaging

pkg of 20 mL

refractive index

n20/D 1.3720 (lit.)

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1 of 4

This Item
12654021.008641.09623
Ethyl Acetate Pharmaceutical Secondary Standard; Certified Reference Material

RTC000087

Ethyl Acetate

Ethyl acetate United States Pharmacopeia (USP) Reference Standard

1265402

Ethyl acetate

Ethyl acetate EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

1.00864

Ethyl acetate

Ethyl acetate for extraction, for analysis EMSURE® ACS,ISO,Reag. Ph Eur

1.09623

Ethyl acetate

application(s)

pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

liquid formulation
pharmaceutical
semi-solid formulation

application(s)

environmental
food and beverages
industrial qc
pharmaceutical
sample preparation

format

neat

format

neat

format

neat

format

neat

Quality Level

300

Quality Level

-

Quality Level

500

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

-

grade

ACS reagent, for analytical purposes, for extraction, reagent grade

storage temp.

2-30°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-30°C

packaging

pkg of 20 mL

packaging

-

packaging

-

packaging

-

General description

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Analysis Note

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB9766 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

EUH066

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

26.6 °F

flash_point_c

-3 °C

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Certificates of Analysis (COA)

Lot/Batch Number

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D Guest et al.
Environmental health perspectives, 57, 177-183 (1984-08-01)
A comparison was made of the absorption and elimination rates of 2-propoxyethyl acetate (PEA) and 2-ethoxyethyl acetate (EEA) following inhalation, dermal application or IV administration. Male beagle dogs were exposed to 50 ppm PEA or EEA for 5 hr, and
Y Kim et al.
Occupational and environmental medicine, 56(6), 378-382 (1999-09-04)
To evaluate exposure to mixed solvents containing ethylene glycol monoethyl ether acetate (EGEEA) in shipyard painters, to determine if EGEEA is toxic to the bone marrow. An industrial hygiene survey was performed to identify exposure to EGEEA of two groups
B D Hardin et al.
Environmental health perspectives, 57, 69-74 (1984-08-01)
Previous NIOSH studies demonstrated the embryo- and fetotoxicity and teratogenicity of ethylene glycol monoethyl ether (EGEE) applied to the shaved skin of pregnant rats. In the present study ethylene glycol monoethyl ether acetate (EGEEA), ethylene glycol monobutyl ether (EGBE), and
J E Doe
Environmental health perspectives, 57, 33-41 (1984-08-01)
An inhalation teratology study was conducted in rats at 10, 50 and 250 ppm ethylene glycol monoethyl ether (EGEE) and in rabbits at 10, 50 and 175 ppm EGEE. This study was designed to supplement a study conducted for NIOSH
M L Gargas et al.
Toxicology and applied pharmacology, 165(1), 63-73 (2000-05-18)
The solvents ethylene glycol monoethyl ether acetate (EGEEA) and ethylene glycol monoethyl ether (EGEE), at sufficiently high doses, are known to be rodent developmental toxicants, exerting their toxic effects through the action of their metabolite 2-ethoxyacetic acid (2-EAA). Thus risks
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