T35955

p-Toluenesulfonyl chloride

reagent grade, ≥98%

• Synonym(s): Tosyl chloride
• Linear Formula: CH₃C₆H₄SO₂Cl
• CAS Number: 98-59-9
• Molecular Weight: 190.65
• Beilstein/REAXYS Number: 607898
• EC Number: 202-684-8
• MDL number: MFCD00007450
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654666
• NACRES: NA.21

Properties

• grade: reagent grade
• Quality Level: 200
• vapor pressure: 1 mmHg ( 88 °C)
• assay: ≥98%
• bp: 134 °C/10 mmHg (lit.)
• mp: 65-69 °C (lit.)
• SMILES string: Cc1ccc(cc1)S(Cl)(=O)=O
• InChI: 1S/C7H7ClO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3
• InChI key: YYROPELSRYBVMQ-UHFFFAOYSA-N

Description

Application

p-toluenesulfonyl chloride may be used along with N-methylimidazole for the esterification or thioesterification of carboxylic acids and alcohols or thiols. It may also be used as a chlorine source for α-chlorination of ketones in the presence of lithium diisopropylamide.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H290,H315,H317,H318
• pcodes: P234 - P261 - P264 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 1
• flash_point_f: 262.4 °F - closed cup
• flash_point_c: 128 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges