26745
Cholesterol Esterase from porcine pancreas
lyophilized, powder, white, ~35 U/mg
Synonym(s):
bile salt-dependent lipase, bile salt-stimulated lipase, carboxyl ester lipase, nonspecific lipase, pancreatic lysophospholipase, Cholesterol Esterase from hog pancreas, Sterol-ester acylhydrolase
About This Item
Recommended Products
biological source
Porcine pancreas
Quality Level
form
powder
quality
lyophilized
specific activity
~35 U/mg
mol wt
Mr ~440000
color
white
storage temp.
−20°C
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This Item | C3766 | 46058 | E0258 |
---|---|---|---|
specific activity ~35 U/mg | specific activity ≥200 units/g protein | specific activity ≥50 U/mg | specific activity ≥4.0 units/mg protein (biuret) |
biological source Porcine pancreas | biological source - | biological source Porcine liver | biological source Porcine pancreas |
form powder | form lyophilized powder | form lyophilized solid, powder | form lyophilized powder |
storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
mol wt Mr ~440000 | mol wt 84 kDa by SDS-PAGE | mol wt Mr ~162000 | mol wt - |
Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
General description
Pancreatic cholesterol esterase (CEase), also known as bile salt stimulated lipase, is a serine hydrolase belonging to the α/β hydrolase family of enzymes.[1] They are released from the exocrine pancreas. Serine 194, histidine 435 and aspartate 320 represent the catalytic triad of the enzyme.[1]
Application
- in an in vitro simulated digestion model to improve the hydrolysis of carotenoid esters in the intestinal phase[2]
- to analyze the bioavailability of phytosterol and cholesterol in the aqueous micellar phase of an in vitro simulated digestion model[3]
- as a standard in enzyme activity assay[4]
Biochem/physiol Actions
Unit Definition
Disclaimer
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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