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Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
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Other Notes
Product not available in all regions or countries. Analyte Specific Reagent. Analytical and performance characteristics are not established. To request more information on this product, please contact technical services at 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Astrid T Stormorken et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23(21), 4705-4712 (2005-07-22)
Hereditary nonpolyposis colorectal cancer (HNPCC) may be caused by mutations in mismatch repair (MMR) genes. The aim of this study was to validate immunohistochemistry and family history as prescreening tools to predict germline mutations in MLH1, MSH2, and MSH6. Pedigrees
Tine Plato Hansen et al.
Applied immunohistochemistry & molecular morphology : AIMM, 14(1), 115-121 (2006-03-17)
Testing for microsatellite instability (MSI) has become an important step in the planning of therapeutic and follow-up procedures for patients with colorectal cancer, both as a prognostic marker and as a screening tool for hereditary non-polyposis colorectal cancer. Today the
D A Lawes et al.
British journal of cancer, 93(4), 472-477 (2005-08-18)
There is increased incidence of microsatellite instability (MSI) in patients who develop multiple primary colorectal cancers (CRC), although the association with hereditary nonpolyposis colon cancer (HNPCC) is unclear. This study aims to evaluate the underlying genetic cause of MSI in
R C Niessen et al.
Gut, 55(12), 1781-1788 (2006-04-26)
Patients with early-onset colorectal cancer (CRC) or those with multiple tumours associated with hereditary non-polyposis colorectal cancer (HNPCC) raise suspicion of the presence of germline DNA mismatch repair (MMR) gene mutations. To analyse the value of family history, microsatellite instability
Kristina Lagerstedt Robinson et al.
Journal of the National Cancer Institute, 99(4), 291-299 (2007-02-22)
Preventive programs for individuals who have high lifetime risks of colorectal cancer may reduce disease morbidity and mortality. Thus, it is important to identify the factors that are associated with hereditary colorectal cancer and to monitor the effects of tailored
Articles
Colorectal cancer is a common occurrence among inhabitants of most Western countries, second only to carcinoma of the lung.
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