30078

Cysteamine hydrochloride

BioXtra

• Synonym(s): β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride
• Linear Formula: HSCH₂CH₂NH₂ · HCl
• CAS Number: 156-57-0
• Molecular Weight: 113.61
• Beilstein/REAXYS Number: 3590083
• EC Number: 205-858-1
• MDL number: MFCD00012904
• UNSPSC Code: 41106305
• PubChem Substance ID: 329753424
• NACRES: NA.51

Properties

• product line: BioXtra
• Quality Level: 200
• pH: 3.5-5.0 (25 °C, 1 M in H₂O)
• mp: 67-71 °C
• solubility: H₂O: 1 m at 20 °C, clear, colorless
• anion traces: sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.5 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤50 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• absorption: cut-off at 270 nm in H₂O at 1 M
• λ: 1 M in H₂O
• UV absorption: λ: 280 nm A_max: ≤0.3
• storage temp.: 2-8°C
• SMILES string: Cl[H].NCCS
• InChI: 1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H
• InChI key: OGMADIBCHLQMIP-UHFFFAOYSA-N

Description

General description

Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine.

Application

Cysteamine is used in a wide range of applications such as regulation of gene expression, depletion of somatostatin and coating of nanoparticles. It may be used to study the potential value of cystine in metabolism disorders such as cystinosis. Cysteamine may be used as a redox sensitive component in biosensor development.

Other Notes

Aminothiol radioprotector; Inducer of duodenal ulcers in rodents; Depletes somatostatin concentration in rat tissues.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319,H335
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves