36105

(±)-Sodium β-hydroxyisobutyrate

≥96.0%

• Synonym(s): β-Hydroxyisobutyric acid sodium salt, (±)-β-HIBA-Na, 3-Hydroxy-2-methylpropionic acid sodium salt, Sodium 3-hydroxy-2-methylpropionate
• Empirical Formula (Hill Notation): C₄H₇NaO₃
• CAS Number: 1219589-99-7
• Molecular Weight: 126.09
• MDL number: MFCD16875405
• UNSPSC Code: 12352106
• PubChem Substance ID: 329755270
• NACRES: NA.25

Properties

• Quality Level: 100
• assay: ≥96.0% (GC); ≥96.0%
• form: powder
• composition: sodium, 17.5-19.0%
• storage temp.: 2-8°C
• SMILES string: [Na+].CC(CO)C([O-])=O
• InChI: 1S/C4H8O3.Na/c1-3(2-5)4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
• InChI key: RBJZIQZDAZLXEK-UHFFFAOYSA-M

Description

Application

3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4).

Biochem/physiol Actions

3-Hydroxyisobutyrate (HIBA), is formed in the valine catabolism[1], it is a reactant of enzyme 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4); it was found to have increased concentrations in MS patient metabolic profiles[2].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable