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36275

Sigma-Aldrich

Lycopene, Redivivo™

10% FS, ~10% in corn oil, ≥95.0% (sum of isomers)

Synonym(s):

Lycopene, dispersion

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About This Item

Empirical Formula (Hill Notation):
C40H56
CAS Number:
502-65-8
Molecular Weight:
536.87
EC Number:
232-281-2
MDL number:
MFCD00017350
UNSPSC Code:
12352211
PubChem Substance ID:
329755000
NACRES:
NA.47
Pricing and availability is not currently available.

Quality Level

100

assay

≥95.0% (sum of isomers)

contains

≤2.5% α-Tocopherol as stabilizer

concentration

~10% in corn oil

storage temp.

2-8°C

SMILES string

C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C

InChI

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

InChI key

OAIJSZIZWZSQBC-GYZMGTAESA-N

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Anti-c-Jun Antibody, clone 1G8 ZooMAb® Rabbit Monoclonal

clone

1G5, monoclonal, recombinant monoclonal

clone

DM1A, recombinant monoclonal

clone

1J8, recombinant monoclonal

clone

1G8, recombinant monoclonal

species reactivity

mouse, rat, human

species reactivity

human, mouse, rat

species reactivity

human

species reactivity

rat, mouse, human

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

UniProt accession no.

P19532

UniProt accession no.

Q71U36

UniProt accession no.

Q86X51

UniProt accession no.

P05412

Biochem/physiol Actions

Lycopene is a red phytochemical pigment found in tomatoes. The main carotenoid in human plasma, it is a highly potent antioxidant, the most efficient biological quencher of singlet oxygen,[1] associated with decreased risk of cancer and cardiovascular diseases. Lycopene enhances gap junction communication between cells via upregulation of connexin 43 and reduces profileration of cancer cells in culture. Inhibits cholesterol synthesis and enhances low-density lipoprotein degradation. Lycopene in skin sacrificially protects against UV-induced degradation of β-carotene.[2]

Other Notes

REDIVIVO is a non-toxic, stable formulation of lycopene (10% dispersion in corn oil) that offers convenient handling and is dust-free.

Legal Information

Redivivo is a trademark of DSM Nutritional Products AG

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCBJ9005V
BCBB1229V
BCBB1229

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USP

USP

1148806

Corn oil

β-Carotene synthetic, ≥93% (UV), powder

Sigma-Aldrich

C9750

β-Carotene

Corn oil analytical standard

Supelco

47112-U

Corn oil

Tamoxifen ≥99%

Sigma-Aldrich

T5648

Tamoxifen

P Di Mascio et al.
Archives of biochemistry and biophysics, 274(2), 532-538 (1989-11-01)
Lycopene, a biologically occurring carotenoid, exhibits the highest physical quenching rate constant with singlet oxygen (kq = 31 X 10(9) M-1 s-1), and its plasma level is slightly higher than that of beta-carotene (kq = 14 X 10(9) M-1 s-1).
Wilhelm Stahl et al.
Skin pharmacology and applied skin physiology, 15(5), 291-296 (2002-09-20)
Upon exposure to UV light photooxidative reactions are initiated which are damaging to biomolecules and affect the integrity of cells and tissues. Photooxidative damage plays a role in pathological processes and is involved in the development of disorders affecting the
J D Ribaya-Mercado et al.
The Journal of nutrition, 125(7), 1854-1859 (1995-07-01)
This placebo-controlled study examined in healthy women the effects of ingestion of a single large dose of beta-carotene (120 mg) on the concentrations of beta-carotene and lycopene in plasma and skin, and the effects of UV light exposure on the
M Porrini et al.
The Journal of nutrition, 130(2), 189-192 (2000-03-17)
Several epidemiologic studies have suggested a role of tomato products in protecting against cancer and chronic diseases. In nine adult women, we evaluated whether the consumption of 25 g tomato puree (containing 7 mg lycopene and 0.3 mg beta-carotene) for
Joanna Lado et al.
Physiologia plantarum, 154(4), 469-484 (2015-02-14)
The distinctive color of red grapefruits is due to lycopene, an unusual carotene in citrus. It has been observed that red 'Star Ruby' (SR) grapefruits grown inside the tree canopy develop a more intense red coloration than those exposed to
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