56968

Sparfloxacin

≥98.0% (HPLC)

• Synonym(s): 5-Amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• Empirical Formula (Hill Notation): C₁₉H₂₂F₂N₄O₃
• CAS Number: 110871-86-8
• Molecular Weight: 392.40
• Beilstein/REAXYS Number: 9170271
• MDL number: MFCD00869619
• UNSPSC Code: 51282944
• PubChem Substance ID: 57651613
• NACRES: NA.85

Properties

• biological source: synthetic
• assay: ≥98.0% (HPLC)
• form: powder
• color: white to light yellow
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria; mycobacteria; mycoplasma
• mode of action: enzyme | inhibits
• SMILES string: C[C@H]1CN(C[C@@H](C)N1)c2c(F)c(N)c3C(=O)C(=CN(C4CC4)c3c2F)C(O)=O
• InChI: 1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+
• InChI key: DZZWHBIBMUVIIW-DTORHVGOSA-N
• Gene Information: human ... KCNH1(3756), TOP2A(7153)

Description

Application

Sparfoxacin is used to study antimicrobial activity against Mycobacteria and respiratory tract infections .

Biochem/physiol Actions

Sparfloxacin fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. It inhibits bacterial DNA gyrase-dependent processes such as DNA polymerization, ATP-dependent-DNA supercoiling, and chromosome fragmentation.

Packaging

1g, 10g

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves