Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

58756

Sigma-Aldrich

1-(5-Isoquinolinesulfonyl)-3-methylpiperazine

≥98.0% (HPLC)

Synonym(s):

1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine, Iso-H-7

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C14H17N3O2S
CAS Number:
84477-73-6
Molecular Weight:
291.37
Beilstein/REAXYS Number:
5445506
MDL number:
MFCD00132900
UNSPSC Code:
12352202
PubChem Substance ID:
57651659
NACRES:
NA.77

Quality Level

100

assay

≥98.0% (HPLC)

form

powder

storage temp.

2-8°C

SMILES string

CC1CN(CCN1)S(=O)(=O)c2cccc3cnccc23

InChI

1S/C14H17N3O2S/c1-11-10-17(8-7-16-11)20(18,19)14-4-2-3-12-9-15-6-5-13(12)14/h2-6,9,11,16H,7-8,10H2,1H3

InChI key

QGSCXAWTTISKLF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Less potent inhibitor of protein kinaseC than H-7

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
333333/1

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

C C Chua et al.
Biochimica et biophysica acta, 1401(2), 187-194 (1998-04-09)
Vascular endothelial growth factor (VEGF) is a potent mitogen for endothelial cells and a vascular permeability factor. In this study we found that the addition of angiotensin II (AII) to rat heart endothelial cells induced VEGF mRNA production. VEGF mRNA
J Duraj et al.
Neoplasma, 44(4), 205-211 (1997-01-01)
The human pre-B acute lymphoblastic leukemia cell line REH6 was utilized for characterization of CD45 glycoprotein by monoclonal antibodies (mAb) recognizing four distinct CD45 antigen specificities, i.e. nonrestricted CD45, restricted CD45RA, CD45RB and CD45R0. Immunoprecipitation revealed two antigen specificities on
K Fujisawa et al.
Placenta, 21(4), 354-360 (2000-06-02)
To clarify the biological and pathological features of choriocarcinoma, we evaluated the in vitro production of cytokines by a choriocarcinoma cell line, BeWo. We measured the concentration of interleukin (IL)-6 and IL-8 in the culture media of BeWo cells after
T Miyashita et al.
Receptors & channels, 7(2), 77-91 (2000-08-22)
We previously reported that the metabotropic glutamate receptor R1alpha (mGluR1alpha) can be activated not only by applying glutamate but also by raising extracellular Ca2+ (Ca2+o) concentration, and that the constant stimulation by Ca2+o causes morphological change of transfected Chinese Hamster
A Symes et al.
The Journal of biological chemistry, 272(15), 9648-9654 (1997-04-11)
Ciliary neurotrophic factor (CNTF)-dependent induction of expression of the neuropeptide vasoactive intestinal peptide (VIP) gene is mediated by a 180-base pair cytokine response element (CyRE) in the VIP promoter. To elucidate the molecular mechanisms mediating the transcriptional activation by CNTF
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service