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903H-0

Sigma-Aldrich

MART-1 (M2-7C10) + Tyrosinase (T311) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

M2-7C10 + T311, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

bottle of 1.0 mL predilute (903H-07)
bottle of 7.0 mL predilute (903H-08)

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1 of 4

This Item
281M-9281M-8904H-0
MART-1 (M2-7C10) + Tyrosinase (T311) Mouse Monoclonal Antibody

903H-0

MART-1 (M2-7C10) + Tyrosinase (T311) Mouse Monoclonal Antibody

MART-1 (Melan A) (M2-7C10) Mouse Monoclonal Antibody

281M-9

MART-1 (Melan A) (M2-7C10) Mouse Monoclonal Antibody

MART-1 (Melan A) (A103) Mouse Monoclonal Antibody

281M-8

MART-1 (Melan A) (A103) Mouse Monoclonal Antibody

HMB-45 + MART-1 (Melan A) + Tyrosinase (HMB-45 + A103 + T311) Mouse Monoclonal Antibody

904H-0

HMB-45 + MART-1 (Melan A) + Tyrosinase (HMB-45 + A103 + T311) Mouse Monoclonal Antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

clone

M2-7C10 + T311, monoclonal

clone

M2-7C10, monoclonal

clone

A103, monoclonal

clone

HMB-45+A103+T311, monoclonal

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

Gene Information

human ... MLANA(2315)

Gene Information

human ... MLANA(2315)

Gene Information

human ... MLANA(2315)

Gene Information

-

General description

MART-1 (also known as Melan A) is a melanocyte differentiation antigen. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Tyrosinase is an enzyme integral in the process of melanin synthesis, and found in 85% to 90% of malignant melanomas. Given these statistics, this cocktail is ideally suited to detection of melanomas and melanocytic lesions.

Quality


IVD
IVD
IVD
RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

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    M R Briejer et al.
    The Journal of pharmacology and experimental therapeutics, 274(2), 641-648 (1995-08-01)
    In the guinea pig proximal colon, 5-hydroxytryptamine (5-HT) stimulates neuronal 5-HT1-like receptors to induce relaxations that are mediated by nitric oxide and ATP. In the current study, the effects of cisapride and structural analogs on these 5-HT-induced relaxations were investigated.
    Mihai Covasa et al.
    American journal of physiology. Regulatory, integrative and comparative physiology, 285(3), R641-R648 (2003-05-31)
    MK-801, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, enhances gastric emptying while increasing food intake. Although our previously reported results implicate the vagus in MK-801's effect on feeding, it is not clear whether vagal motor fibers participate in the feeding response.
    Atsuko Inui et al.
    Japanese journal of pharmacology, 90(4), 313-320 (2002-12-26)
    It is known that 5-HT(4) receptors in the colon of guinea pigs show a distribution similar to that in humans. Thus, we examined the effects of mosapride citrate (mosapride) and cisapride, two 5-HT(4)-receptor agonists, on colonic motility in conscious guinea
    Haruka Nishimuta et al.
    The AAPS journal, 21(2), 20-20 (2019-01-24)
    Accurate prediction of human pharmacokinetics for drugs remains challenging, especially for non-cytochrome P450 (P450) substrates. Hepatocytes might be suitable for predicting hepatic intrinsic clearance (CLint) of new chemical entities, because they can be applied to various compounds regardless of the
    Henry C Liu et al.
    The Journal of pharmacology and experimental therapeutics, 359(1), 215-229 (2016-08-05)
    Statistical analysis was performed on physicochemical descriptors of ∼250 drugs known to interact with one or more SLC22 "drug" transporters (i.e., SLC22A6 or OAT1, SLC22A8 or OAT3, SLC22A1 or OCT1, and SLC22A2 or OCT2), followed by application of machine-learning methods
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