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A3281

Sigma-Aldrich

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride

Synonym(s):

W-7

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About This Item

Empirical Formula (Hill Notation):
C16H21ClN2O2S · HCl
CAS Number:
61714-27-0
Molecular Weight:
377.33
Beilstein/REAXYS Number:
6030174
MDL number:
MFCD00012559
UNSPSC Code:
12352200
PubChem Substance ID:
24278067
NACRES:
NA.77
Pricing and availability is not currently available.

form

powder

Quality Level

200

mode of action

cell membrane | interferes
enzyme | inhibits

storage temp.

−20°C

SMILES string

Cl[H].NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12

InChI

1S/C16H21ClN2O2S.ClH/c17-15-9-5-8-14-13(15)7-6-10-16(14)22(20,21)19-12-4-2-1-3-11-18;/h5-10,19H,1-4,11-12,18H2;1H

InChI key

OMMOSRLIFSCDBL-UHFFFAOYSA-N

Gene Information

human ... CAMK2A(815), CAMK2B(816)

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1 of 4

This Item
SML0657681629GF37370752
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride

A3281

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride

N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride ≥98% (HPLC)

SML0657

N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride

W-7, Hydrochloride A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC₅₀ = 51 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC₅₀ = 28 µM).

681629

W-7, Hydrochloride

Tungsten powder, max. particle size 25 micron, weight 1000 g, purity 99.9%

GF37370752

Tungsten

form

powder

form

powder or crystals

form

crystalline solid

form

powder

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

-

mode of action

cell membrane | interferes

mode of action

-

mode of action

-

mode of action

-

Gene Information

human ... CAMK2A(815), CAMK2B(816)

Gene Information

-

Gene Information

-

Gene Information

-

Application

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride has been used to study its effect of on coated pit staining.[1]

Biochem/physiol Actions

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) is a calmodulin antagonist. It can prevent calcium-dependent protein kinase, that is sensitive to phospholipid.[2]

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLBR5186V
    SLBM7616V
    SLBC0044V
    031M5007V
    031M5007

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