A5226

Angiopoietin-1 human

≥90% (SDS-PAGE), recombinant, expressed in NSO cells

• Synonym(s): Ang-1
• MDL number: MFCD04040129
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• recombinant: expressed in NSO cells
• Quality Level: 100
• assay: ≥90% (SDS-PAGE)
• form: solid
• UniProt accession no.: Q15389
• storage temp.: −20°C
• Gene Information: human ... ANGPT1(284)

Description

Biochem/physiol Actions

Ang-1 is a ligand with affinity to the Tie-2 receptor tyrosine kinase, which is expressed in early hematopoietic and endothelial cells. Both Ang-1 and Tie-2 play critical roles in embryonic angiogenesis as well as adult vascular integrity.

Ligand with affinity to the Tie-2 receptor tyrosine kinase. Both Ang-1 and Tie-2 play critical roles in embryonic angiogenesis as well as adult vascular integrity.

Physical form

Lyophilized from a 0.2 μm filtered solution in 50 mM Tris and 0.5 M sodium chloride, pH 6.5, containing 50 μg bovine serum albumin per 1 μg of cytokine.

Analysis Note

The biological activity is measured by its ability to inhibit serum deprivation induced apoptosis in HUVE cells.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable