A5879

2-(2-Aminoethyl)isothiourea dihydrobromide

• Synonym(s): 2-(2-Aminoethyl)-2-thiopseudourea dihydrobromide, AET, S-(2-Aminoethyl)isothiouronium bromide hydrobromide
• Linear Formula: NH₂CH₂CH₂SC(=NH)NH₂ · 2HBr
• CAS Number: 56-10-0
• Molecular Weight: 281.01
• Beilstein/REAXYS Number: 3911163
• EC Number: 200-257-0
• MDL number: MFCD00037011
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278229
• NACRES: NA.77

Properties

• assay: ≥98% (TLC)
• Quality Level: 100
• form: powder
• mp: 190-196 °C (lit.)
• solubility: water: 50 mg/mL, clear to very slightly hazy, colorless to yellow
• SMILES string: Br[H].Br[H].NCCSC(N)=N
• InChI: 1S/C3H9N3S.2BrH/c4-1-2-7-3(5)6;;/h1-2,4H2,(H3,5,6);2*1H
• InChI key: XDVMCVGTDUKDHL-UHFFFAOYSA-N
• Gene Information: human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

Description

Application

2-(2-Aminoethyl)isothiourea dihydrobromide inhibits nitric oxide synthase (NOS).

Biochem/physiol Actions

Inhibits constitutive and inducible NOS.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves