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Key Documents

ABK0016

Sigma-Aldrich

UsteBridge ELISA Kit from rabbit serum

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32
Pricing and availability is not currently available.

antibody form

purified immunoglobulin

species reactivity

human (IgG)

shipped in

wet ice

storage temp.

2-8°C

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This Item
MABF3175MABF3179MABF2299
Anti-IL-4 Antibody, clone 2D7.14.8

MABF3181

Anti-IL-4 Antibody, clone 2D7.14.8

Anti-IL-5 Antibody, clone 4A1.6.15

MABF3175

Anti-IL-5 Antibody, clone 4A1.6.15

Anti-IL-6 Antibody, clone 3A7.10

MABF3179

Anti-IL-6 Antibody, clone 3A7.10

Anti-IL-1α Antibody, clone 7E5.14.5

MABF2299

Anti-IL-1α Antibody, clone 7E5.14.5

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

Gene Information

mouse ... IL4(3565)

Gene Information

mouse ... IL5(3567)

Gene Information

mouse ... IL6(3569)

Gene Information

-

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

clone

2D7.14.8, monoclonal

clone

4A1.6.15, monoclonal

clone

3A7.10, monoclonal

clone

7E5.14.5, monoclonal

General description

A Protein Conformational Array (PCA) in a sandwich ELISA format where the plate is coated with a panel of antibodies raised against peptides derived from the full length protein sequence of Ustekinumab. Taken individually, each of these antibodies is strongly antigenic to the peptide sequence that was used in its production. However, when these peptides are incorporated into a full length correctly folded protein, the antigenicity of many of them is masked by the three dimensional structure of the protein and only a limited number of the antibodies respond. The result is a histogram which can be likened to a ‘fingerprint′ for correctly folded Ustekinumab. For a Stelara Biosimilar, if the protein is correctly folded and glycosylated, the ‘fingerprint′ will match that of Ustekinumab. If it is not correctly folded, previously masked peptide sequences will be exposed and will be recognized by the antibody made to that exposed sequence. In this way, changes in the ‘fingerprint′ generated by the ELISA will point out differences between the Biosimilar and authentic Ustekinumab.

Application

For research use only. Not for use in diagnostic procedures.

Other Notes

ELISA kit contains 3 96-well microplates and all the components necessary to complete an ELISA test.

pictograms

Corrosion
GHS05

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

Storage Class

8A - Combustible corrosive hazardous materials

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