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AV41212

Sigma-Aldrich

Anti-SF1 (AB1) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Splicing factor 1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

68 kDa

species reactivity

rabbit, mouse, human, rat, bovine, dog, horse, guinea pig

concentration

0.5 mg - 1 mg/mL

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Anti-KLK3 antibody produced in rabbit Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

HPA000764

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Anti-Kallikrein-3 (KLK3) (CT) Antibody from rabbit

AB10428

Anti-Kallikrein-3 (KLK3) (CT) Antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

saturated ammonium sulfate (SAS) precipitated

UniProt accession no.

P07288

UniProt accession no.

-

UniProt accession no.

P07288

UniProt accession no.

P07288

Gene Information

human ... KLK3(354)

Gene Information

human ... KLK3(354)

Gene Information

human ... KLK3(354)

Gene Information

human ... KLK3(354)

Immunogen

Synthetic peptide directed towards the C terminal region of human SF1

Biochem/physiol Actions

SF1 contains 1 KH domain and 1 CCHC-type zinc finger. It is necessary for the ATP-dependent first step of spliceosome assembly and binds to the intron branch point sequence (BPS) 5′-UACUAAC-3′ of the pre-mRNA. It may act as transcription repressor.

Sequence

Synthetic peptide located within the following region: MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTM

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    QC9946

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    Single-nucleotide polymorphism rs1058205 of KLK3 is associated with the risk of prostate cancer: A case-control study of Han Chinese men in Northeast China.
    Chen C and Xin Z
    Medicine, 96(10) (2017)
    Keke Zhang et al.
    Molecular medicine reports, 17(6), 8203-8211 (2018-04-17)
    The androgen receptor (AR) has a crucial role in prostate cancer. RNA‑binding protein‑mediated post‑transcriptional regulation is important in the initiation and development of cancer. The present study attempted to elucidate the mutual association of AR and RNA‑binding protein quaking (QKI)
    Eric G Bluemn et al.
    Cancer cell, 32(4), 474-489 (2017-10-11)
    Androgen receptor (AR) signaling is a distinctive feature of prostate carcinoma (PC) and represents the major therapeutic target for treating metastatic prostate cancer (mPC). Though highly effective, AR antagonism can produce tumors that bypass a functional requirement for AR, often
    Pavlo L Kovalenko et al.
    The Journal of surgical research, 190(1), 177-184 (2014-04-29)
    Schlafen proteins have previously been linked to leukocyte and intestinal epithelial differentiation. We hypothesized that Schlafen 12 (SLFN12) overexpression in human prostate epithelial cells would modulate expression of prostate-specific antigen (PSA) and dipeptidyl peptidase 4 (DPP4), markers of prostatic epithelial
    Seung-Yon Lee et al.
    Cancer letters, 354(2), 390-397 (2014-09-10)
    Metformin, a diabetes drug, has been reported to inhibit the growth of prostate cancer cells. In this study, we investigated the effect and action mechanism of metformin on the function of androgen receptor (AR), a key molecule in the proliferation

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