B1552

Bromoenol lactone

≥98% (TLC)

• Synonym(s): BEL, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one
• Empirical Formula (Hill Notation): C₁₆H₁₃BrO₂
• CAS Number: 88070-98-8
• Molecular Weight: 317.18
• MDL number: MFCD00270871
• UNSPSC Code: 41106300
• PubChem Substance ID: 24278257
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• assay: ≥98% (TLC)
• form: powder
• potency: 636 nM K_i
• solubility: DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.); degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
• λmax: 224 nm
• storage temp.: −20°C
• SMILES string: [H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23
• InChI: 1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
• InChI key: BYUCSFWXCMTYOI-ZRDIBKRKSA-N

Description

Biochem/physiol Actions

Potent, irreversible inhibitor of calcium-independent phospholipase A₂ and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC₅₀ = 8 μM); enzyme activated irreversible chymotrypsin inhibitor (K_i = 636 nM).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves