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B1651

Sigma-Aldrich

Bradykinin Fragment 1-7

≥97% (HPLC)

Synonym(s):

1-7-Bradykinin

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About This Item

Empirical Formula (Hill Notation):
C35H52N10O9
CAS Number:
Molecular Weight:
756.85
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
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Product Name

Bradykinin Fragment 1-7, ≥97% (HPLC)

Quality Level

assay

≥97% (HPLC)

form

powder

color

white

UniProt accession no.

storage temp.

−20°C

SMILES string

NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O

InChI

1S/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)

InChI key

CRROPKNGCGVIOG-UHFFFAOYSA-N

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro

General description

Bradykinin fragment 1-7 (BK-(1-7)), an endogenous peptide, is present in plasma.

Application

Bradykinin Fragment 1-7 has been used as an external calibrant/standard in the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis of protein spots.
Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s).

Biochem/physiol Actions

Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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