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C111080

Sigma-Aldrich

DMT-dC(bz) Phosphoramidite

configured for PerkinElmer, configured for Polygen

Synonym(s):

Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], DMT-dC(bz) amidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-?bis(1-methylethyl)phosphoramidite], N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

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About This Item

Empirical Formula (Hill Notation):
C46H52N5O8P
CAS Number:
102212-98-6
Molecular Weight:
833.91
MDL number:
MFCD00036315
UNSPSC Code:
41116107
PubChem Substance ID:
329774852
NACRES:
NA.51
Pricing and availability is not currently available.

biological source

non-animal source (no BSE/TSE risk)

Quality Level

200

type

for DNA synthesis

product line

Proligo Reagents

assay

≥99% (31P-NMR)
≥99.0% (reversed phase HPLC)

form

powder or granules

technique(s)

oligo synthesis: suitable

impurities

≤0.3 wt. % water content (Karl Fischer)

color

white to off-white

λ

conforms (UV/VIS Identity)

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suitability

suitable for (fluorescent; luminescent assays)

suitability

suitable for (fluorescent; luminescent assays)

suitability

suitable for (fluorescent; luminescent assays)

suitability

suitable for (fluorescent; luminescent assays)

size

1536 wells

size

1536 wells

size

1536 wells

size

1536 wells

sterility

sterile

sterility

non-sterile

sterility

sterile

sterility

non-sterile

feature

lid

feature

lid: no, skirt

feature

lid, plate format: low base

feature

lid: no, skirt

packaging

pkg of 10 ea

packaging

pkg of 10 ea, case of 50 ea

packaging

pkg of 10 ea, case of 50 ea

packaging

pack of 10, case of 50

General description

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites:
  • Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
  • The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides
The product belongs to Expedite™ synthesizers.

Legal Information

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    HMBJ3463
    HMBJ2978
    HMBJ2193
    HMBJ2588
    HMBJ2540

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