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C4733

Sigma-Aldrich

BID, Caspase-8-cleaved from mouse

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution

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About This Item

MDL number:
MFCD03456214
UNSPSC Code:
12352202
NACRES:
NA.32
Pricing and availability is not currently available.

recombinant

expressed in E. coli

Quality Level

200

assay

≥95% (SDS-PAGE)

form

buffered aqueous solution

UniProt accession no.

P70444

shipped in

dry ice

storage temp.

−20°C

Gene Information

mouse ... Bid(12122)

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BID, Caspase-8-cleaved from mouse ≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution

C4733

BID, Caspase-8-cleaved from mouse

Caspase 8 human ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine tagged), buffered aqueous solution, ≥1,000 units/mg protein

C1099

Caspase 8 human

Anti-mouse BID cleavage (59/60) site specific Antibody Chemicon®, from rabbit

AB10002

Anti-mouse BID cleavage (59/60) site specific Antibody

Caspase 3 human ≥85% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein

C1224

Caspase 3 human

assay

≥95% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

-

assay

≥85% (SDS-PAGE)

recombinant

expressed in E. coli

recombinant

expressed in E. coli (C-terminal histidine tagged)

recombinant

-

recombinant

expressed in E. coli (C-terminal histidine-tagged)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

form

buffered aqueous solution

form

buffered aqueous solution

form

-

form

buffered aqueous glycerol solution

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

shipped in

dry ice

UniProt accession no.

P70444

UniProt accession no.

Q14790

UniProt accession no.

P70444

UniProt accession no.

P42574

General description

Mouse BID cleaved with caspase-8 generates the amino-terminal fragment (amino acids 1-59, 7 kDa) and the carboxy-terminal fragment (amino acids 60-195, 15 kDa). On size exclusion chromatography cleaved BID elutes at 27 kDa indicating that the fragments remain associated.

Biochem/physiol Actions

Caspase-8-cleaved BID relocates from the cytosol to the outer mitochondrial membrane where its interaction with Bak alters mitochondrial membrane permeability.

Physical form

0.2 μm filtered solution in 25 mM HEPES, pH 7.5, and 0.1 M KCl.

Analysis Note

Measured by its ability to induce cytochrome c release from isolated mouse liver mitochondria.

Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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