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Key Documents

C8863

Sigma-Aldrich

7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine

≥98% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C23H22N4O
CAS Number:
Molecular Weight:
370.45
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: soluble 17 mg/mL at ≤60 °C

storage temp.

2-8°C

SMILES string

Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C5CCCC5

InChI

1S/C23H22N4O/c24-22-21-20(14-27(17-6-4-5-7-17)23(21)26-15-25-22)16-10-12-19(13-11-16)28-18-8-2-1-3-9-18/h1-3,8-15,17H,4-7H2,(H2,24,25,26)

InChI key

FMETVQKSDIOGPX-UHFFFAOYSA-N

Gene Information

Biochem/physiol Actions

A potent and selective pyrrolo[2,3-d]pyrimidine Lck inhibitor.
Potent and selective inhibitor of Lck, a src family tyrosine kinase.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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