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D0815

Sigma-Aldrich

2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide

≥99% purity (HPLC), solid

Synonym(s):

DASPEI

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About This Item

Empirical Formula (Hill Notation):
C17H21IN2
CAS Number:
3785-01-1
Molecular Weight:
380.27
Beilstein/REAXYS Number:
3783243
EC Number:
223-248-3
MDL number:
MFCD00011994
UNSPSC Code:
12171500
PubChem Substance ID:
329798640
NACRES:
NA.47
Pricing and availability is not currently available.

Product Name

2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide, ≥99% (HPLC), solid

Quality Level

100

assay

≥99% (HPLC)

form

solid

color

red

mp

267 °C (dec.) (lit.)

solubility

DMSO: 0.5 mg/mL
methanol: soluble

εmax

36.0-41.0 at 457-463 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

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This Item
D1065D8064E18905
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide ≥99% (HPLC), solid

D0815

2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide

4-(2-[6-(Dioctylamino)-2-naphthalenyl]ethenyl)-1-(3-sulfopropyl)pyridinium inner salt ≥95% (HPLC), solid

D1065

4-(2-[6-(Dioctylamino)-2-naphthalenyl]ethenyl)-1-(3-sulfopropyl)pyridinium inner salt

4-(2-(6-(Dibutylamino)-2-naphthalenyl)ethenyl)-1-(3-sulfopropyl)pyridinium hydroxide inner salt ≥95% (HPLC), solid

D8064

4-(2-(6-(Dibutylamino)-2-naphthalenyl)ethenyl)-1-(3-sulfopropyl)pyridinium hydroxide inner salt

Ethyl(2E)-2-cyano-3-(1H-indolyl-3-yl)acrylate 99%

E18905

Ethyl(2E)-2-cyano-3-(1H-indolyl-3-yl)acrylate

color

red

color

orange to red

color

orange to dark red

color

yellow

solubility

DMSO: 0.5 mg/mL, methanol: soluble

solubility

DMSO: soluble, ethanol: soluble

solubility

DMF: soluble, DMSO: soluble, ethanol: soluble

solubility

methanol: 2.5%

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

solid

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

Application

2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) has been used for the labelling of hair cells in larval zebrafish.[1]

Biochem/physiol Actions

2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) accumulates in the mitochondria and has a large fluorescence Stokes shift. It is also used for the relative measurements of mitochondrial membrane potential.[2]
Suitable as a mitochondrial stain in live cells.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCQ7413
    MKCL7116
    MKCK9474
    MKCK3632
    MKCJ2640

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    Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.
    Vlasits AL, et al.
    Hearing Research, 294, 153-165 (2012)
    W Armand Guiguemde et al.
    Nature, 465(7296), 311-315 (2010-05-21)
    Malaria caused by Plasmodium falciparum is a disease that is responsible for 880,000 deaths per year worldwide. Vaccine development has proved difficult and resistance has emerged for most antimalarial drugs. To discover new antimalarial chemotypes, we have used a phenotypic
    Marina Yoffe et al.
    Journal of experimental zoology. Part B, Molecular and developmental evolution, 334(7-8), 511-517 (2020-05-22)
    The lateral line is the primary modality fish use to create a hydrodynamic image of their environment. These images contribute to a variety of behaviors, from rheotaxis to escape responses. Here we discern the contributions of visual and lateral line
    Ru Zhang et al.
    Biomolecules, 10(10) (2020-10-22)
    Cochlear hair cells in human beings cannot regenerate after loss; however, those in fish and other lower species can. Recently, the role of inflammation in hair cell regeneration has been attracting the attention of scientists. In the present study, we
    Development of a no-wash assay for mitochondrial membrane potential using the styryl dye DASPEI.
    Jensen KH and Rekling JC
    Journal of Biomolecular Screening, 15, 1071-1081 (2010)
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