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D1641

Sigma-Aldrich

Dihydrocytochalasin B

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About This Item

Empirical Formula (Hill Notation):
C29H39NO5
CAS Number:
39156-67-7
Molecular Weight:
481.62
EC Number:
254-324-4
MDL number:
MFCD12910542
UNSPSC Code:
12352202
PubChem Substance ID:
24893505
NACRES:
NA.32
Pricing and availability is not currently available.

form

powder

Quality Level

200

storage temp.

−20°C

SMILES string

C[C@@H]1CCC[C@@H](O)CCC(=O)O[C@]23[C@@H](\C=C\C1)[C@H](O)C(=C)[C@@H](C)[C@H]2[C@H](Cc4ccccc4)NC3=O

InChI

1S/C29H39NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14,18-19,22-24,26-27,31,33H,3,7,9-10,13,15-17H2,1-2H3,(H,30,34)/b14-8+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1

InChI key

WIULKAASLBZREV-RXPQEOCGSA-N

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Show Differences

1 of 4

This Item
SML3043SML3526SML3641
Linagliptin ≥98% (HPLC)

SML3619

Linagliptin

XL188 ≥98% (HPLC)

SML3043

XL188

AZD8529 ≥98% (HPLC)

SML3526

AZD8529

Volasertib ≥95% (HPLC)

SML3641

Volasertib

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

solubility

DMSO: 2 mg/mL, clear (Warmed)

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear (Warmed)

color

white to beige

color

white to beige

color

white to beige

color

white to beige

Application

Marker for high affinity cytochalasin B binding sites.

Biochem/physiol Actions

Effect on cell motility and morphology similar to that of cytochalasin B; does not inhibit glucose transport.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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    Certificates of Analysis (COA)

    Lot/Batch Number
    049M4002V
    058M4024V
    076M4026V
    085M4028V
    14150909

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    K Kovacs et al.
    Virchows Archiv. A, Pathological anatomy and histology, 395(1), 59-68 (1982-01-01)
    A pituitary adenoma removed by surgery from a 22-year-old man was studied by histology, immunocytology, transmission electron microscopy and immunoelectron microscopy. Clinically, the patient had acromegaly and euthyroidism with elevated blood GH concentrations. Blood TSH and T4 levels were within
    A Matsuno et al.
    Pathology, research and practice, 197(1), 13-20 (2001-02-24)
    To characterize the morphological and functional aspects of silent somatotroph adenomas with paradoxical responses of GH in TRH or GnRH provocation tests, which are considered to be a useful strategy for endocrinological identification of silent somatotroph adenomas, we examined three
    L K Chopin et al.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 12(2), 126-136 (2002-08-15)
    Prostate cancer is a significant cause of morbidity and mortality in Western males. While it is known that androgens play a central role in prostate cancer development and progression, other hormones and growth factors are also involved in prostate growth.
    T Fukaya et al.
    Cancer, 45(7), 1598-1603 (1980-04-01)
    In attempting to establish a functional classification of acidophilic adenomas of the pituitary gland, immunoperoxidase staining techniques specific for growth hormone (GH), prolactin (PRL), and luteinizing hormone (LH) were carried out. Surgically removed specimens from 24 acromegalic patients were studied.
    T García-Caballero et al.
    Endocrine, 12(3), 265-271 (2000-08-30)
    The liver is an essential target tissue for growth hormone (GH) and prolactin (PRL). The aim of this study was to determine the in situ expression of growth hormone receptor (GHR) and prolactin receptor (PRLR) in hepatocellular carcinomas and to
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