D3630
Diphenhydramine hydrochloride
≥98% (HPLC)
Synonym(s):
2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride
About This Item
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
powder
originator
Johnson & Johnson
SMILES string
Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2
InChI
1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
InChI key
PCHPORCSPXIHLZ-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
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Related Categories
1 of 4
This Item | Z743264 | Z743263 | Z743261 |
|---|---|---|---|
| packaging pack of 1 ea | packaging pack of 1 ea | packaging pack of 1 ea | packaging pack of 1 ea |
| manufacturer/tradename Julabo 8930410 | manufacturer/tradename Julabo 8930413 | manufacturer/tradename Julabo 8930412 | manufacturer/tradename Julabo 8930425 |
| I.D. × L 14 mm × 1 m , for use with 8-10 mm I.D. reinforced tubing | I.D. × L 23 mm × 1 m , for use with 1/2 inch I.D. reinforced tubing | I.D. × L 18 mm × 1 m , for use with 12 mm I.D. reinforced tubing | I.D. × L 35 mm × 1 m , for use with 1 inch I.D. reinforced tubing |
Application
as a reference compound to study the long duration of action of antihistamine bilastine in vivo[1]
to detect its embryotoxicity by embryonic stem cell test (EST) using cardiomyocyte differentiation[2] and osteoblasts differentiation[3]
as an antihistamine in experimental studies[4][5]
Biochem/physiol Actions
Diphenhydramine hydrochloride (DPH) is an antihistaminic agent that relieves symptoms of hypersensitive reactions.[6][7] It exhibits antimuscarinic and marked sedative effects.[8] DPH is also used to prevent nausea, vomiting and vertigo of various causes.[6] In addition, it acts as a potential therapeutic for insomnia.[7]
Features and Benefits
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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