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E0251

Sigma-Aldrich

Estrone 3-sulfate sodium salt

contains ~35% Tris as stabilizer

Synonym(s):

1,3,5(10)-Estratrien-17-one 3-sulfate

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About This Item

Linear Formula:
C18H21O5SNa
CAS Number:
438-67-5
Molecular Weight:
372.41
MDL number:
MFCD00070035
UNSPSC Code:
12352202
PubChem Substance ID:
24894364
NACRES:
NA.77
Pricing and availability is not currently available.

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥98% (TLC)

form

powder

contains

~35% Tris as stabilizer

technique(s)

inhibition assay: suitable

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

−20°C

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This Item
430609447226331937
Lanthanum(III) isopropoxide 98%

665193

Lanthanum(III) isopropoxide

Lanthanum(III) trifluoromethanesulfonate 99.999% trace metals basis

430609

Lanthanum(III) trifluoromethanesulfonate

Lanthanum(III) hydroxide 99.9% trace metals basis

447226

Lanthanum(III) hydroxide

Lanthanum(III) nitrate hexahydrate 99.99% trace metals basis

331937

Lanthanum(III) nitrate hexahydrate

reaction suitability

core: lanthanum, reagent type: catalyst

reaction suitability

core: lanthanum, reagent type: catalyst

reaction suitability

-

reaction suitability

-

assay

98%

assay

99.999% trace metals basis

assay

99.9% trace metals basis

assay

99.99% trace metals basis

form

solid

form

-

form

powder

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

Package size based on steroid content

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    086M4083V
    085M4170V
    099M4044V
    13181143
    088M4146V

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    E S M Silva et al.
    Theriogenology, 86(7), 1749-1756 (2016-08-09)
    The present study evaluated the influence of different regimens of estradiol benzoate (EB) treatments followed by a single dose of long-acting progesterone (LA P4) on plasma estrogen and P4 concentrations in noncyclic mares prepared as embryo recipients. Twenty-one anestrous mares
    Christopher A Pearl et al.
    Domestic animal endocrinology, 33(4), 451-459 (2006-10-13)
    The steroid hormone regulation of the epididymis in a high estrogen producing animal like the boar is not currently understood. To test the hypothesis that the boar epididymis is an estrogen and androgen responsive tissue, the presence of estrogen and
    Takashi Nozawa et al.
    Pharmaceutical research, 22(10), 1634-1641 (2005-09-24)
    The aim of the study is to suppress the progress of estrogen-dependent breast cancer by inhibiting the membrane transporter, which mediates the internalization of estrone-3-sulfate as estrogen precursor in the cancer cells. The uptake of estrone-3-sulfate by estrogen-dependent breast cancer
    Maria Karlgren et al.
    Journal of medicinal chemistry, 55(10), 4740-4763 (2012-05-01)
    The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are involved in many clinical drug-drug interactions. Predicting potential interactions with OATPs is, therefore, of value. Here, we developed in vitro and in silico models
    Anna Koenen et al.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(4), 774-780 (2012-09-18)
    Previously, the steroid hormone progesterone has been demonstrated to stimulate OATP2B1-mediated transport of estrone-3-sulphate (E(1)S), dehydroepiandrosterone sulphate (DHEAS) and pregnenolone sulphate (PS), which may influence the uptake of precursor molecules for steroid hormone synthesis. However, it is unclear whether OATP2B1
    View All Related Papers

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